Olivier Britz

TL;DR: In this article, intersectional genetic manipulations were used to identify the critical components of pain transduction in the spinal cord, including spinal SOM(+) excitatory and inhibitory neurons, coupled with behavioral and electrophysiological analysis.

TL;DR: These studies reveal a dedicated spinal cord inhibitory pathway that gates the transmission of mechanical itch, a chronic itch state that is histamine-independent and is transmitted independently of neurons that express the gastrin-releasing peptide receptor.

TL;DR: This work shows that the production of an alternating flexor-extensor motor rhythm depends on the composite activities of two classes of ventrally located inhibitory neurons, V1 and V2b interneurons (INs).

TL;DR: It is argued that the RORα INs direct corrective reflex movements by integrating touch information with descending motor commands from the cortex and cerebellum, and are innervated by corticospinal and vestibulospinal projection neurons.

TL;DR: The subset of somatostatin-lineage neurons preserved in VT3Lbx1-neuron-ablated mice is largely sufficient to mediate morphine-sensitive and morphine-resistant forms of von Frey filament-evoked punctate mechanical hypersensitivity.