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Eric Frank

Researcher at Tufts University

Publications -  19
Citations -  1258

Eric Frank is an academic researcher from Tufts University. The author has contributed to research in topics: Spinal cord & Artemin. The author has an hindex of 14, co-authored 19 publications receiving 1144 citations.

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Neurotrophin 3 supports the survival of developing muscle sensory neurons in culture

TL;DR: Direct evidence is provided for a potential role of NT-3 versus NGF in the survival of a specific subpopulation of DRG neurons and suggests that muscle sensory neurons, which are probably more prevalent at the cervical and lumbar levels, may be specifically affected byNT-3.
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Pax6 and Engrailed 1 Regulate Two Distinct Aspects of Renshaw Cell Development

TL;DR: It is shown that a subset of V1 INs differentiates as Renshaw cells, the interneuronal cell type that mediates recurrent inhibition of motor neurons, and that Pax6 and En1 have essential roles in establishing the recurrent inhibitory circuit between motor neurons and Rensaw cells.
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V1 and V2b Interneurons Secure the Alternating Flexor-Extensor Motor Activity Mice Require for Limbed Locomotion

TL;DR: This work shows that the production of an alternating flexor-extensor motor rhythm depends on the composite activities of two classes of ventrally located inhibitory neurons, V1 and V2b interneurons (INs).
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Restoration of Visual Function by Enhancing Conduction in Regenerated Axons.

TL;DR: Ass analyses suggest that regenerated axons fail to conduct action potentials from the eye to the SC due to lack of myelination and administration of voltage-gated potassium channel blockers restores conduction and results in increased visual acuity.
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Persistent restoration of sensory function by immediate or delayed systemic artemin after dorsal root injury.

TL;DR: Systemic artemin administration produced essentially complete and persistent restoration of nociceptive and sensorimotor functions, and could represent a promising therapy that may effectively promote sensory neuronal regeneration and functional recovery after injury.