E
Eric Frank
Researcher at Tufts University
Publications - 19
Citations - 1258
Eric Frank is an academic researcher from Tufts University. The author has contributed to research in topics: Spinal cord & Artemin. The author has an hindex of 14, co-authored 19 publications receiving 1144 citations.
Papers
More filters
Journal ArticleDOI
Neurotrophin 3 supports the survival of developing muscle sensory neurons in culture
TL;DR: Direct evidence is provided for a potential role of NT-3 versus NGF in the survival of a specific subpopulation of DRG neurons and suggests that muscle sensory neurons, which are probably more prevalent at the cervical and lumbar levels, may be specifically affected byNT-3.
Journal ArticleDOI
Pax6 and Engrailed 1 Regulate Two Distinct Aspects of Renshaw Cell Development
Tamar Sapir,Eric J. Geiman,Zhi Wang,Tomoko Velasquez,Sachiko Mitsui,Yoshihiro Yoshihara,Eric Frank,Francisco J. Alvarez,Martyn Goulding +8 more
TL;DR: It is shown that a subset of V1 INs differentiates as Renshaw cells, the interneuronal cell type that mediates recurrent inhibition of motor neurons, and that Pax6 and En1 have essential roles in establishing the recurrent inhibitory circuit between motor neurons and Rensaw cells.
Journal ArticleDOI
V1 and V2b Interneurons Secure the Alternating Flexor-Extensor Motor Activity Mice Require for Limbed Locomotion
Jingming Zhang,Guillermo M. Lanuza,Guillermo M. Lanuza,Olivier Britz,Zhi Wang,Valerie C. Siembab,Ying Zhang,Tomoko Velasquez,Francisco J. Alvarez,Francisco J. Alvarez,Eric Frank,Martyn Goulding +11 more
TL;DR: This work shows that the production of an alternating flexor-extensor motor rhythm depends on the composite activities of two classes of ventrally located inhibitory neurons, V1 and V2b interneurons (INs).
Journal ArticleDOI
Restoration of Visual Function by Enhancing Conduction in Regenerated Axons.
Fengfeng Bei,Henry H.C. Lee,Xuefeng Liu,Georgia Gunner,Hai Jin,Long Ma,Chen Wang,lijun Hou,Takao K. Hensch,Eric Frank,Joshua R. Sanes,Chinfei Chen,Michela Fagiolini,Zhigang He +13 more
TL;DR: Ass analyses suggest that regenerated axons fail to conduct action potentials from the eye to the SC due to lack of myelination and administration of voltage-gated potassium channel blockers restores conduction and results in increased visual acuity.
Journal ArticleDOI
Persistent restoration of sensory function by immediate or delayed systemic artemin after dorsal root injury.
Ruizhong Wang,Tamara King,Michael H. Ossipov,Anthony Rossomando,Todd W. Vanderah,Pamela A. Harvey,Peter Cariani,Eric Frank,Dinah W. Y. Sah,Dinah W. Y. Sah,Frank Porreca +10 more
TL;DR: Systemic artemin administration produced essentially complete and persistent restoration of nociceptive and sensorimotor functions, and could represent a promising therapy that may effectively promote sensory neuronal regeneration and functional recovery after injury.