O
Olivier Salvado
Researcher at Commonwealth Scientific and Industrial Research Organisation
Publications - 316
Citations - 11999
Olivier Salvado is an academic researcher from Commonwealth Scientific and Industrial Research Organisation. The author has contributed to research in topics: Cognitive decline & Dementia. The author has an hindex of 45, co-authored 310 publications receiving 9943 citations. Previous affiliations of Olivier Salvado include Cooperative Research Centre & University of Queensland.
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Journal ArticleDOI
Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study.
Victor L. Villemagne,Samantha C. Burnham,Pierrick Bourgeat,Belinda M. Brown,Kathryn A. Ellis,Olivier Salvado,Cassandra Szoeke,S. Lance Macaulay,Ralph N. Martins,Paul Maruff,David Ames,Christopher C. Rowe,Colin L. Masters +12 more
TL;DR: These projections suggest a prolonged preclinical phase of AD in which Aβ deposition reaches the authors' threshold of positivity at 17·0 (95% CI 14·9-19·9) years, hippocampal atrophy at 4·2 (3·6-5·1] years, and memory impairment at 3·3 (2·5-4·5) years before the onset of dementia (clinical dementia rating score 1).
Journal ArticleDOI
Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging
Christopher C. Rowe,Kathryn A. Ellis,Kathryn A. Ellis,Miroslava Rimajova,Pierrick Bourgeat,Kerryn E. Pike,Gareth Jones,Jurgen Fripp,Henri Tochon-Danguy,Laurence Morandeau,Graeme O'Keefe,Roger I. Price,Parnesh Raniga,Peter Robins,Oscar Acosta,Nat Lenzo,Cassandra Szoeke,Olivier Salvado,Richard Head,Ralph N. Martins,Colin L. Masters,David Ames,Victor L. Villemagne +22 more
TL;DR: PiB binding in AD was unrelated to age, hippocampal volume or memory, and secondary factors or downstream events appear to play a more direct role than total beta amyloid burden in hippocampal atrophy and cognitive decline.
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Longitudinal Assessment of Aβ and Cognition in Aging and Alzheimer Disease
Victor L. Villemagne,Kerryn E. Pike,Gaël Chételat,Kathryn A. Ellis,Rachel S. Mulligan,Pierrick Bourgeat,Uwe Ackermann,Gareth Jones,Cassandra Szoeke,Olivier Salvado,Ralph N. Martins,Graeme O'Keefe,Chester A. Mathis,William E. Klunk,David Ames,Colin L. Masters,Christopher C. Rowe +16 more
TL;DR: Assess Aβ deposition longitudinally and explore its relationship with cognition and disease progression.
Journal ArticleDOI
Apparent Fibre Density: a novel measure for the analysis of diffusion-weighted magnetic resonance images.
David Raffelt,Jacques-Donald Tournier,Stephen E. Rose,Gerard R. Ridgway,Robert D. Henderson,Stuart Crozier,Olivier Salvado,Alan Connelly +7 more
TL;DR: This article presents and evaluates a novel method to modulate the FOD to account for changes in fibre bundle cross-sectional area that occur during spatial normalisation, and describes a novel approach for statistical analysis of AFD that uses cluster-based inference of differences extended throughout space and orientation.
Journal ArticleDOI
Relationship between atrophy and beta-amyloid deposition in Alzheimer disease.
Gaël Chételat,Victor L. Villemagne,Pierrick Bourgeat,Kerryn E. Pike,Gareth Jones,David Ames,Kathryn A. Ellis,Cassandra Szoeke,Ralph N. Martins,Graeme O'Keefe,Olivier Salvado,Colin L. Masters,Christopher C. Rowe +12 more
TL;DR: In this article, the role of aggregated beta-amyloid in relation to gray matter atrophy is investigated and correlations between global and regional neocortical PiB retention and atrophy were analyzed in each clinical group.