K
Kathryn A. Ellis
Researcher at University of Melbourne
Publications - 233
Citations - 18150
Kathryn A. Ellis is an academic researcher from University of Melbourne. The author has contributed to research in topics: Cognitive decline & Dementia. The author has an hindex of 60, co-authored 226 publications receiving 15215 citations. Previous affiliations of Kathryn A. Ellis include University of Western Australia & Florey Institute of Neuroscience and Mental Health.
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Journal ArticleDOI
Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study.
Victor L. Villemagne,Samantha C. Burnham,Pierrick Bourgeat,Belinda M. Brown,Kathryn A. Ellis,Olivier Salvado,Cassandra Szoeke,S. Lance Macaulay,Ralph N. Martins,Paul Maruff,David Ames,Christopher C. Rowe,Colin L. Masters +12 more
TL;DR: These projections suggest a prolonged preclinical phase of AD in which Aβ deposition reaches the authors' threshold of positivity at 17·0 (95% CI 14·9-19·9) years, hippocampal atrophy at 4·2 (3·6-5·1] years, and memory impairment at 3·3 (2·5-4·5) years before the onset of dementia (clinical dementia rating score 1).
Journal ArticleDOI
A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease
Frank Jessen,Frank Jessen,Rebecca E. Amariglio,Martin P.J. van Boxtel,Monique M.B. Breteler,Mathieu Ceccaldi,Gaël Chételat,Bruno Dubois,Carole Dufouil,Kathryn A. Ellis,Wiesje M. van der Flier,Lidia Glodzik,Argonde C. van Harten,Mony J. de Leon,Pauline McHugh,Michelle M. Mielke,José Luis Molinuevo,Lisa Mosconi,Ricardo S. Osorio,Audrey Perrotin,Ronald C. Petersen,Laura A. Rabin,Lorena Rami,Barry Reisberg,Dorene M. Rentz,Perminder S. Sachdev,Vincent de La Sayette,Andrew J. Saykin,Philip Scheltens,Melanie B. Shulman,Melissa J. Slavin,Reisa A. Sperling,Robert Stewart,Olga Uspenskaya,Bruno Vellas,Pieter Jelle Visser,Pieter Jelle Visser,Michael Wagner,Michael Wagner +38 more
TL;DR: Research criteria for SCD in pre‐mild cognitive impairment (MCI) are presented and a list of core features proposed for reporting in SCD studies is provided, which will enable comparability of research across different settings.
A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease
Frank Jessen,Frank Jessen,Rebecca E. Amariglio,Martin P.J. van Boxtel,Monique M.B. Breteler,Mathieu Ceccaldi,Gaël Chételat,Bruno Dubois,Carole Dufouil,Kathryn A. Ellis,Wiesje M. van der Flier,Lidia Glodzik,Argonde C. van Harten,Mony J. de Leon,Pauline McHugh,Michelle M. Mielke,José Luis Molinuevo,Lisa Mosconi,Ricardo S. Osorio,Audrey Perrotin,Ronald C. Petersen,Laura A. Rabin,Lorena Rami,Barry Reisberg,Dorene M. Rentz,Perminder S. Sachdev,Vincent de La Sayette,Andrew J. Saykin,Philip Scheltens,Melanie B. Shulman,Melissa J. Slavin,Reisa A. Sperling,Robert Stewart,Olga Uspenskaya,Bruno Vellas,Pieter Jelle Visser,Pieter Jelle Visser,Michael Wagner,Michael Wagner +38 more
TL;DR: In this paper, research criteria for subjective cognitive decline in individuals with unimpaired performance on cognitive tests may represent the first symptomatic manifestation of Alzheimer's disease (AD) are presented.
Journal ArticleDOI
Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging
Christopher C. Rowe,Kathryn A. Ellis,Kathryn A. Ellis,Miroslava Rimajova,Pierrick Bourgeat,Kerryn E. Pike,Gareth Jones,Jurgen Fripp,Henri Tochon-Danguy,Laurence Morandeau,Graeme O'Keefe,Roger I. Price,Parnesh Raniga,Peter Robins,Oscar Acosta,Nat Lenzo,Cassandra Szoeke,Olivier Salvado,Richard Head,Ralph N. Martins,Colin L. Masters,David Ames,Victor L. Villemagne +22 more
TL;DR: PiB binding in AD was unrelated to age, hippocampal volume or memory, and secondary factors or downstream events appear to play a more direct role than total beta amyloid burden in hippocampal atrophy and cognitive decline.
Journal ArticleDOI
Longitudinal Assessment of Aβ and Cognition in Aging and Alzheimer Disease
Victor L. Villemagne,Kerryn E. Pike,Gaël Chételat,Kathryn A. Ellis,Rachel S. Mulligan,Pierrick Bourgeat,Uwe Ackermann,Gareth Jones,Cassandra Szoeke,Olivier Salvado,Ralph N. Martins,Graeme O'Keefe,Chester A. Mathis,William E. Klunk,David Ames,Colin L. Masters,Christopher C. Rowe +16 more
TL;DR: Assess Aβ deposition longitudinally and explore its relationship with cognition and disease progression.