O
Omar Boutureira
Researcher at Rovira i Virgili University
Publications - 79
Citations - 3387
Omar Boutureira is an academic researcher from Rovira i Virgili University. The author has contributed to research in topics: Glycosylation & Catalysis. The author has an hindex of 23, co-authored 73 publications receiving 2783 citations. Previous affiliations of Omar Boutureira include University of Cambridge & University of Oxford.
Papers
More filters
Journal ArticleDOI
Advances in Chemical Protein Modification
TL;DR: This work is funded by the European Commission (Marie Curie CIG) and Ministerio de Ciencia e Innovacion, Spain (Juan de la Cierva Fellowship).
Journal ArticleDOI
Site-selective protein-modification chemistry for basic biology and drug development
Nikolaus Krall,Filipa P. da Cruz,Omar Boutureira,Gonçalo J. L. Bernardes,Gonçalo J. L. Bernardes +4 more
TL;DR: The most exciting current and future applications of chemical site-selective protein modification are highlighted and which hurdles still need to be overcome for more widespread use are considered.
Journal ArticleDOI
Methods for converting cysteine to dehydroalanine on peptides and proteins
Justin M. Chalker,Smita B. Gunnoo,Omar Boutureira,Stefanie Gerstberger,Marta Fernández-González,Gonçalo J. L. Bernardes,Laura Griffin,Hanna Hailu,Christopher J. Schofield,Benjamin G. Davis +9 more
TL;DR: The most general method investigated—a bis-alkylation–elimination of cysteine to dehydroalanine—was applied successfully to multiple proteins and enabled the site-selective synthesis of a glycosylated antibody.
Journal ArticleDOI
Uptake of unnatural trehalose analogs as a reporter for Mycobacterium tuberculosis
Keriann M. Backus,Keriann M. Backus,Helena I. Boshoff,Conor S. Barry,Omar Boutureira,Mitul Patel,Francois D'Hooge,Seung Seo Lee,Laura E. Via,Kapil Tahlan,Clifton E. Barry,Benjamin G. Davis +11 more
TL;DR: It is shown here that Ag85 enzymes have exceptionally broad substrate specificity, which allowed exogenously added synthetic probes to be specifically incorporated into M. tuberculosis growing in vitro and within macrophages.
Journal ArticleDOI
QuaNCAT: quantitating proteome dynamics in primary cells
Andrew J. M. Howden,Andrew J. M. Howden,Vincent Geoghegan,Kristin Katsch,Georgios Efstathiou,Bhaskar Bhushan,Omar Boutureira,Omar Boutureira,Benjamin Thomas,David C. Trudgian,David C. Trudgian,Benedikt M. Kessler,Daniela C. Dieterich,Daniela C. Dieterich,Benjamin G. Davis,Oreste Acuto +15 more
TL;DR: In this article, the power of Bio-Orthogonal Non Canonical Amino acid Tagging (BONCAT) and Stable Isotope Labelling of Amino acids in Cell culture (SILAC) was combined to monitor the early expression changes of > 600 proteins in primary resting T cells subjected to activation stimuli.