O
Omar H. Cabrera
Researcher at Anschutz Medical Campus
Publications - 17
Citations - 959
Omar H. Cabrera is an academic researcher from Anschutz Medical Campus. The author has contributed to research in topics: Medicine & Sevoflurane. The author has an hindex of 8, co-authored 13 publications receiving 798 citations. Previous affiliations of Omar H. Cabrera include University of Colorado Denver & University of Missouri–St. Louis.
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Journal ArticleDOI
Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise.
Jonathan J. Miner,Bin Cao,Jennifer Govero,Amber M. Smith,Estefania Fernandez,Omar H. Cabrera,Charise Garber,Michelle Noll,Robyn S. Klein,Kevin K. Noguchi,Indira U. Mysorekar,Michael S. Diamond +11 more
TL;DR: These models will facilitate the study of ZIKV pathogenesis, in utero transmission, and testing of therapies and vaccines to prevent congenital malformations and to identify ZikV within trophoblasts of the maternal and fetal placenta, consistent with a trans-placental infection route.
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Isoflurane exposure leads to apoptosis of neurons and oligodendrocytes in 20- and 40-day old rhesus macaques
Katie J. Schenning,Kevin K. Noguchi,Lauren D. Martin,Francesca M. Manzella,Omar H. Cabrera,Gregory A. Dissen,Ansgar M. Brambrink +6 more
TL;DR: The present data suggest that the window of vulnerability for neurons is beginning to close in the P20 and P40 rhesus macaques, but continuing for oligodendrocytes.
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Sevoflurane-Induced Dysregulation of Cation-Chloride Cotransporters NKCC1 and KCC2 in Neonatal Mouse Brain.
TL;DR: It is hypothesized that anesthetics may dysregulate NKCC1 and/or KCC2 in developing brain and contribute to neurodevelopmental impairments the authors have observed in previous studies of neonatal anesthesia exposure.
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Caffeine combined with sedative/anesthetic drugs triggers widespread neuroapoptosis in a mouse model of prematurity
Omar H. Cabrera,Shawn O'Connor,Brant S. Swiney,Patricia Salinas-Contreras,Francesca M. Manzella,George T. Taylor,Kevin K. Noguchi +6 more
TL;DR: CAF may augment the neurotoxic action of SADs indicated for neonatal sedation/anesthesia in the NICU by triggering widespread apoptosis in the developing brains of premature infants by causing more neurotoxicity than expected.
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Sex differences in neurodevelopmental abnormalities caused by early-life anaesthesia exposure: a narrative review
TL;DR: An emerging pattern of potential sex-dependent neurodevelopmental abnormalities in rodent models of human infant anaesthesia exposure is presented, and sex differences in the field of anaesthesia-induced developmental neurotoxicity are reviewed.