O
Orazio Valsecchi
Researcher at Armed Forces Institute of Pathology
Publications - 65
Citations - 3507
Orazio Valsecchi is an academic researcher from Armed Forces Institute of Pathology. The author has contributed to research in topics: Stent & Drug-eluting stent. The author has an hindex of 22, co-authored 65 publications receiving 3339 citations.
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Journal ArticleDOI
Localized Hypersensitivity and Late Coronary Thrombosis Secondary to a Sirolimus-Eluting Stent: Should We Be Cautious?
Renu Virmani,Giulio Guagliumi,Andrew Farb,Giuseppe Musumeci,Niccolò Grieco,Teresio Motta,Laurian Mihalcsik,Maurizio Tespili,Orazio Valsecchi,Frank D. Kolodgie +9 more
TL;DR: The known pharmacokinetic elution profile of Cypher stents and the presence of polymer fragments surrounded by giant cells and eosinophils suggest that a reaction to the polymer may have caused late stent thrombosis.
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Examination of the in vivo mechanisms of late drug-eluting stent thrombosis: findings from optical coherence tomography and intravascular ultrasound imaging.
Giulio Guagliumi,Vasile Sirbu,Giuseppe Musumeci,Robert Gerber,Giuseppe Biondi-Zoccai,Hideyuki Ikejima,Elena Ladich,Nikoloz Lortkipanidze,Aleksandre Matiashvili,Orazio Valsecchi,Renu Virmani,Gregg W. Stone +11 more
TL;DR: The presence of uncovered stent struts as assessed by OCT and positive vessel remodeling as imaged by IVUS were associated with LST after drug-eluting stent (DES) implantation with optical coherence tomography (OCT).
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Failure of transradial approach during coronary interventions: Anatomic considerations
Orazio Valsecchi,Angelina Vassileva,Giuseppe Musumeci,Roberta Rossini,Maurizio Tespili,Giulio Guagliumi,Laurian Mihalcsik,Antonello Gavazzi,Paolo Ferrazzi +8 more
TL;DR: Angiography of the arteries of the upper limb to delineate the anatomic features of the radial artery as a way to determine the feasibility of using it as a route for coronary intervention and overall procedural success by transradial approach was 97.5%.
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Optical Coherence Tomography Assessment of In Vivo Vascular Response After Implantation of Overlapping Bare-Metal and Drug-Eluting Stents
Giulio Guagliumi,Giuseppe Musumeci,Vasile Sirbu,Hiram G. Bezerra,Nobuaki Suzuki,Luigi Fiocca,Aleksandre Matiashvili,Nikoloz Lortkipanidze,Antonio Trivisonno,Orazio Valsecchi,Giuseppe Biondi-Zoccai,Marco A. Costa +11 more
TL;DR: The impact of DES on vascular healing was similar at overlapping and nonoverlapping sites, however, strut malapposition, coverage pattern, and neointimal hyperplasia differ significantly according to DES type.
Journal ArticleDOI
Strut Coverage and Late Malapposition With Paclitaxel-Eluting Stents Compared With Bare Metal Stents in Acute Myocardial Infarction Optical Coherence Tomography Substudy of the Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI) Trial
Giulio Guagliumi,Marco A. Costa,Vasile Sirbu,Giuseppe Musumeci,Hiram G. Bezerra,Nobuaki Suzuki,Aleksandre Matiashvili,Nikoloz Lortkipanidze,Laurian Mihalcsik,Antonio Trivisonno,Orazio Valsecchi,Gary S. Mintz,Ovidiu Dressler,Helen Parise,Akiko Maehara,Ecaterina Cristea,Alexandra J. Lansky,Roxana Mehran,Gregg W. Stone +18 more
TL;DR: In patients with STEMI undergoing primary percutaneous coronary intervention, implantation of PES as compared with BMS significantly reduces neointimal hyperplasia but results in higher rates of uncovered and malapposed stent struts as assessed by optical coherence tomography at 13-month follow-up.