Orestis Efthimiou

TL;DR: Marked differences exist between antipsychotics in terms of metabolic side-effects, with olanzapine and clozapine exhibiting the worst profiles and aripiprazole, brexpiprazoles, cariprazine, lurasidone, and ziprasidone the most benign profiles.

TL;DR: In this article, the authors conducted a systematic review and IPD network meta-analysis and estimated relative treatment effect sizes across different patient characteristics through IPD-network meta-regression, and found that both guided and unguided iCBT were associated with more effectiveness as measured by PHQ-9 scores than control treatments over the short term and the long term.

TL;DR: A literature review as mentioned in this paper provides an overview of methods for performing an individual participant data meta-analysis (IPD-MA) using evidence from clinical trials or non-randomized studies when investigating treatment efficacy.

TL;DR: A review of the relevant literature on NMA methodology aiming to pinpoint the developments that have appeared in the field can be found in this article, where the authors present a review of several applications, methodological developments, and empirical studies in NMA, and the area is thriving as its relevance to public health is increasingly recognized.

TL;DR: Why rare events require special attention in meta-analysis is discussed, an overview of some approaches suitable for meta-analysing rare events are presented, and practical recommendations for their use are provided.