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Showing papers in "The Lancet Psychiatry in 2020"



Journal ArticleDOI
TL;DR: The 2019 novel coronavirus (2019-nCoV) pneumonia, believed to have originated in a wet market in Wuhan, Hubei province, China at the end of 2019, has gained intense attention nationwide and globally and a range of measures has been urgently adopted.

2,447 citations


Journal ArticleDOI
TL;DR: The systematic review and meta-analysis revealed that during the acute illness, common symptoms among patients admitted to hospital for SARS or MERS included confusion and depression, and in one study traumatic memories.

1,701 citations


Journal ArticleDOI
TL;DR: Mental health in the UK had deteriorated compared with pre-COVID-19 trends by late April, 2020, and policies emphasising the needs of women, young people and those with preschool aged children are likely to play an important part in preventing future mental illness.

1,636 citations


Journal ArticleDOI
TL;DR: The COVID-19 crisis has laid bare the preexisting conditions of modern society: inequality, workers’ rights violations, air pollution, and biodiversity loss, to climate change.

1,534 citations


Journal ArticleDOI
TL;DR: The present work provides a rationale based approach for the selection of drugs with potential antiviral activity for SARS-CoV-2 infection better than the investigational drug/divdivRemdesivir and other antiviral drugs/drug combinations being evaluated.

1,394 citations



Journal ArticleDOI
TL;DR: The coronavirus disease 2019 (COVID-19) epidemic has now spread across China for over a month, and Xiang and colleagues, claim that the mental health needs of patients with confirmed CO VID-19, patients with suspected infection, quarantined family members, and medical personnel have been poorly handled.

1,244 citations



Journal ArticleDOI
Aravinthan Varatharaj1, Aravinthan Varatharaj2, Naomi Thomas3, Mark Ellul4, Mark Ellul5, Mark Ellul6, Nicholas W. S. Davies, Thomas A Pollak7, Elizabeth L Tenorio8, Mustafa Sultan3, Ava Easton6, Gerome Breen7, Michael S. Zandi9, Jonathan P. Coles10, Hadi Manji9, Rustam Al-Shahi Salman11, David K. Menon10, Timothy R Nicholson7, Laura A Benjamin9, Laura A Benjamin6, Alan Carson11, Craig J. Smith12, Martin R Turner13, Tom Solomon6, Tom Solomon5, Tom Solomon4, Rachel Kneen5, Rachel Kneen6, Sarah Pett14, Ian Galea2, Ian Galea1, Rhys H. Thomas15, Rhys H. Thomas3, Benedict D Michael6, Benedict D Michael5, Benedict D Michael4, Claire Allen, Neil Archibald, James Arkell, Peter Arthur-Farraj, Mark R. Baker, Harriet A. Ball, Verity Bradley-Barker, Zoe Brown, Stefania Bruno, Lois Carey, Christopher Carswell, Annie Chakrabarti, James Choulerton, Mazen Daher, Ruth Davies, Rafael Di Marco Barros, Sofia Dima, Rachel Dunley, Dipankar Dutta, Richard James Booth Ellis, Alex Everitt, Joseph Fady, Patricia Fearon, Leonora Fisniku, Ivie Gbinigie, Alan Gemski, Emma Gillies, Effrossyni Gkrania-Klotsas, Julie Grigg, Hisham Hamdalla, Jack Hubbett, Neil Hunter, Anne-Catherine Huys, Ihmoda Ihmoda, Sissi Ispoglou, Ashwani Jha, Ramzi Joussi, Dheeraj Kalladka, Hind Khalifeh, Sander Kooij, Guru Kumar, Sandar Kyaw, Lucia Li, Edward Littleton, Malcolm R. Macleod, Mary Joan MacLeod, Barbara Madigan, Vikram Mahadasa, Manonmani Manoharan, Richard Marigold, Isaac Marks, Paul M. Matthews, Michael Mccormick, Caroline Mcinnes, Antonio Metastasio, Philip Milburn-McNulty, Clinton Mitchell, Duncan Mitchell, Clare Morgans, Huw R. Morris, Jasper M. Morrow, Ahmed Mubarak Mohamed, Paula Mulvenna, Louis Murphy, Robert Namushi, Edward J Newman, Wendy Phillips, Ashwin Pinto, David A Price, Harald Proschel, Terry Quinn, Deborah Ramsey, Christine Roffe, Amy L Ross Russell, Neshika Samarasekera, Stephen Sawcer, Walee Sayed, Lakshmanan Sekaran, Jordi Serra-Mestres, Victoria K. Snowdon, Gayle Strike, James Sun, Christina Tang, Mark Vrana, Ryckie G. Wade, Chris Wharton, Lou Wiblin, Iryna Boubriak, Katie Herman, Gordon T. Plant 
TL;DR: This is the first nationwide, cross-specialty surveillance study of acute neurological and psychiatric complications of COVID-19 and provides valuable and timely data that are urgently needed by clinicians, researchers, and funders.

990 citations


Journal ArticleDOI
TL;DR: The promise of targeting the inflammation pathway in the management of this challenging condition is today somewhat weaker, but this might not be the last word on the potential role of anti-inflammatory drugs in the treatment of bipolar depression.

Journal ArticleDOI
TL;DR: The interconnectedness of the world made society vulnerable to this infection, but it also provides the infrastructure to address previous system failings by disseminating good practices that can result in sustained, efficient, and equitable delivery of mental health-care delivery.





Journal ArticleDOI
TL;DR: It is shown that the concept of resilience is best understood as the process of multiple biological, psychological, social, and ecological systems interacting in ways that help individuals to regain, sustain, or improve their mental wellbeing when challenged by one or more risk factors.




Journal ArticleDOI
TL;DR: A novel, conservative approach is proposed to the recognition of possible, probable, and definite autoimmune psychoses for use in psychiatric practice and the ethical issues posed by this challenging diagnostic category are discussed.

Journal ArticleDOI
TL;DR: Recommendations are that insomnia is assessed routinely in the occurrence of mental health disorders; that sleep disturbance is treated in services as a problem in its own right, yet also recognised as a pathway to reduce other mental health difficulties; and that access to evidence-based treatment for sleep difficulties is expanded in mental health services.

Journal ArticleDOI
TL;DR: Public mental health interventions (panel) are even more important during pandemics to prevent the anticipated higher prevalence of mental disorders, the associated consequences, and poor mental wellbeing.

Journal ArticleDOI
TL;DR: Patients with a severe mental illness had a slightly higher risk for severe clinical outcomes of COVID-19 than patients without a history of mental illness and diagnosis of a mental illness was not associated with increased likelihood of testing positive for SARS-CoV-2.

Journal ArticleDOI
Emma C. Johnson1, Ditte Demontis2, Thorgeir E. Thorgeirsson, Raymond K. Walters3, Renato Polimanti4, Alexander S. Hatoum1, Sandra Sanchez-Roige5, Sarah E. Paul1, Frank R. Wendt4, Toni-Kim Clarke6, Dongbing Lai7, Gunnar W Reginsson, Hang Zhou4, June He1, David A.A. Baranger8, Daniel F. Gudbjartsson, Robbee Wedow3, Daniel E. Adkins9, Amy E. Adkins9, Jeffry Alexander9, Silviu-Alin Bacanu9, Tim B. Bigdeli10, Joseph M. Boden11, Sandra A. Brown5, Kathleen K. Bucholz1, Jonas Bybjerg-Grauholm12, Robin P. Corley13, Louisa Degenhardt14, Danielle M. Dick9, Benjamin W. Domingue15, Louis Fox1, Alison Goate16, Scott D. Gordon17, Laura M. Hack15, Dana B. Hancock18, Sarah M. Hartz1, Ian B. Hickie19, David M. Hougaard12, Kenneth Krauter13, Penelope A. Lind17, Jeanette N. McClintick7, Matthew B. McQueen13, Jacquelyn L. Meyers10, Grant W. Montgomery20, Ole Mors21, Preben Bo Mortensen2, Merete Nordentoft22, John F. Pearson11, Roseann E. Peterson9, Maureen Reynolds8, John P. Rice1, Valgerdur Runarsdottir, Nancy L. Saccone1, Richard Sherva23, Judy L. Silberg9, Ralph E. Tarter8, Thorarinn Tyrfingsson, Tamara L. Wall5, Bradley T. Webb9, Thomas Werge24, Leah Wetherill7, Margaret J. Wright20, Stephanie Zellers25, Mark Adams6, Laura J. Bierut1, Jason D. Boardman13, William E. Copeland26, Lindsay A. Farrer23, Tatiana Foroud7, Nathan A. Gillespie9, Richard A. Grucza1, Kathleen Mullan Harris27, Andrew C. Heath1, Victor Hesselbrock28, John K. Hewitt13, Christian J. Hopfer29, John Horwood11, William G. Iacono25, Eric O. Johnson18, Kenneth S. Kendler9, Martin A. Kennedy11, Henry R. Kranzler30, Pamela A. F. Madden1, Hermine H. Maes9, Brion S. Maher31, Nicholas G. Martin17, Matt McGue25, Andrew M. McIntosh6, Sarah E. Medland17, Elliot C. Nelson1, Bernice Porjesz10, Brien P. Riley9, Michael C. Stallings13, Michael M. Vanyukov8, Scott I. Vrieze25, Lea K. Davis32, Ryan Bogdan1, Joel Gelernter4, Howard J. Edenberg7, Kari Stefansson33, Anders D. Børglum2, Arpana Agrawal1 
TL;DR: These findings support the theory that Cannabis use disorder has shared genetic liability with other psychopathology, and there is a distinction between genetic liability to cannabis use and cannabis use disorder.

Journal ArticleDOI
TL;DR: This pragmatic, parallel-arm, multicentre randomised controlled trial aimed to compare the effectiveness of cognitive behavioural therapy (CBT) plus standardisedmedical care with standardised medical care alone for the reduction of dissociative seizure frequency.




Journal ArticleDOI
TL;DR: This Review critically evaluates PET imaging results of inflammation in psychiatric disorders, including major depressive disorder, schizophrenia and psychosis disorders, substance use, and obsessive-compulsive disorder.