O
Oriano Mecarelli
Researcher at Sapienza University of Rome
Publications - 126
Citations - 2687
Oriano Mecarelli is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Epilepsy & Electroencephalography. The author has an hindex of 26, co-authored 114 publications receiving 2121 citations. Previous affiliations of Oriano Mecarelli include Policlinico Umberto I.
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Journal ArticleDOI
High prevalence of spontaneous portal-systemic shunts in persistent hepatic encephalopathy: a case-control study.
Oliviero Riggio,Cesare Efrati,Carlo Catalano,Federica Pediconi,Oriano Mecarelli,Neri Accornero,Francesca Nicolao,S. Angeloni,Andrea Masini,Lorenzo Ridola,Adolfo Francesco Attili,Manuela Merli +11 more
TL;DR: It is suggested that large spontaneous shunts may often sustain the chronicity of HE; the presence of large shunts should be sought in patients with cirrhosis with recurrent or persistent HE.
Journal ArticleDOI
Mutations in the GABA Transporter SLC6A1 Cause Epilepsy with Myoclonic-Atonic Seizures
Gemma L. Carvill,Jacinta M McMahon,Amy L Schneider,Matthew Zemel,Candace T. Myers,Julia Saykally,John Nguyen,Angela Robbiano,Federico Zara,Nicola Specchio,Oriano Mecarelli,R Smith,Richard J. Leventer,Rikke S. Møller,Marina Nikanorova,Petia Dimova,Albena Jordanova,Steven Petrou,Ingo Helbig,Pasquale Striano,Sarah Weckhuysen,Samuel F. Berkovic,Ingrid E. Scheffer,Heather C. Mefford +23 more
TL;DR: Target resequencing of 644 individuals with epileptic encephalopathies led to the identification of six SLC6A1 mutations in seven individuals, all of whom have epilepsy with myoclonic-atonic seizures (MAE), accounting for ~4% of unsolved MAE cases.
Journal ArticleDOI
Neurophysiological investigations of hepatic encephalopathy: ISHEN practice guidelines.
Jean-Michel Guerit,Aldo Amantini,C. Fischer,Peter W. Kaplan,Oriano Mecarelli,Alfons Schnitzler,Emilio Ubiali,Piero Amodio +7 more
TL;DR: Clinical neurophysiology can complement the neurological examination to provide evidence of HE in patients who have normal consciousness and to demonstrate the worsening or, conversely improvement, of He in the follow‐up period.
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Epilepsy Care in the Time of COVID-19 Pandemic in Italy: Risk Factors for Seizure Worsening
Giovanni Assenza,Jacopo Lanzone,Francesco Brigo,Antonietta Coppola,Giancarlo Di Gennaro,Vincenzo Di Lazzaro,Lorenzo Ricci,Andrea Romigi,Mario Tombini,Oriano Mecarelli +9 more
TL;DR: During the current COVID-19 pandemic, a significant percentage of people with epilepsy (PwE) experienced difficulties in follow-up and a seizure number increase, in particular those chronically taking more ASMs and with poor sleep quality.
Journal ArticleDOI
Behavioral and electrographic patterns induced by systemic administration of kainic acid in developing rats.
TL;DR: The different sensitivity of systemic KA to induce limbic seizures in neonatal rats may be related to the immaturity of pre- and post-synaptic glutamergic receptors in the hippocampus, which accounts for the preferential activation of the cortex versus hippocampus during the first period of life.