Showing papers in "Developmental Brain Research in 1983"

TL;DR: It is concluded that exogenous NGF can affect forebrain cholinergic neurons during their development and does not seem to be identical with an endogenous neurotrophic factor produced by hippocampus or neocortex acting on cholinerential neurons of the forebrain.

TL;DR: The time-course of development of acetylcholinesterase fiber staining within the hippocampal formation parallels the pattern of innervation by the septal nuclei as demonstrated with amino acid autoradiography, though it lags behind the latter by approximately 5 days.

TL;DR: Subculturing of NGF-treated cells for 10 days demonstrated that gangliosides treatment also enhanced the NGF stimulated regeneration of neurites, suggesting that gang liosides may be incorporated at the level of cell surface, thereby affecting and facilitating membrane phenomena involved in neurite outgrowth.

TL;DR: The present results support the hypothesis that both insulin and IGF stimulate mitotic activity by interacting with specific somatomedin receptors and suggest a physiological role of IGF in the developing brain.

TL;DR: Interference with normal functioning either of AS per se or of specific monoaminergic transmitter systems during early development can produce long-lasting behavioral as well as brain morphological and biochemical abnormalities in later life.

TL;DR: The beneficial effect of high potassium on nerve cell survival was most prominent after 7 DIV, when it is known that transmission-associated neurochemical functions are just becoming detectable under the standard conditions.

TL;DR: There was a greater variability of interspike intervals during firing in motor units from very young animals than in adults and in adult animals it was possible to discern a graded recruitment of motor units.

TL;DR: The use of NC/1 is reported herein to identify crest cells during their migration to their site of final localization, which may shed light on how the neural crest derived mesectoderm and the peripheral nervous system segregate from one another since theNC/1-defined antigen becomes restricted to the cells of the latter.

TL;DR: In this paper, it was shown that the life span of the clusters in the occipital white matter corresponds to the period when transitory callosal axons are eliminated, and ultrastructural observations show groups of axons completely surrounded by gitter cell cytoplasm as if they were being phagocytosed.

TL;DR: The existence of a significant ipsilateral retinofugal component early in development, probably accounts, in part, for the distinctive and persistent ipsilaterally projection that occurs if one eye is removed during the first few days of incubation.

TL;DR: It was possible, however, to induce in female or neonatally castrated male rats a fiber density as high as in control males by high doses of testosterone, given in the first, second or even third week of life.

TL;DR: Evidence is provided that 'numerical matching' occurs between the presynaptic granule cell population and its postsynaptic target, the Purkinje cell, in the cerebellum.

TL;DR: The finding of ‘transitional’ cells with cytological, ultrastructural and immunohistochemical features intermediate between those of astroglial and oligodendroglials cells and the close relationship that develops between astrogLial cells and axons just prior to the onset of myelination suggest that oligodENDroglia may also be derived from radial glial cells, either directly or through intermediate astrognial forms.

TL;DR: Much of the changes in the development of synapses involved asymmetric axo-spinous synapses, with a small reduction in the number of symmetric synapses chiefly in lamina IV.

TL;DR: The results of this study suggest that some topographical features of the normal spinal cord may be represented in mature spinal cord transplants, and establish a basis for future investigations aimed at repair of the injured host spinal cord with homologous fetal tissue.

TL;DR: Astrocyte differentiation in vitro closely resembles that in vivo, and both vimentin-containing and glial filament protein (GFP)-containing intermediate filaments (IF) are present in the small normal fibrous astrocytes as well as in the larger reactive astroCytes.

TL;DR: Comparison of the developmental patterns of glutamine synthetase and S- 100 protein showed that the maximum acquisition of both these astrocytic proteins occurs at a comparable age; however, the former continues to increase for a much longer time than the S-100 protein.

TL;DR: The results show that monocular deprivation is more effective in the experimental animals than in normal kittens of the same age, but less effective than innormal 2-month-old animals.

TL;DR: Using immunocytochemistry, tyrosine hydroxylase-containing cells in the developing inferior colliculus were detected and these cells lacked other catecholamine-synthesizing enzymes and they occurred in newborn and immature rats up to 21 days of age.

TL;DR: Adult patterns and the development of the nucleus of origin of centrifugal innervation of the retina, the nucleus olfacto-retinalis (NOR), were studied with horseradish peroxidase in 2 cichlid fish species to suggest the only known centrifugally projecting nucleus in vertebrates which lacks extensive degenerating patterns during early development.

TL;DR: Injections of horseradish peroxidase into the occipital cortex of the kitten and diffusing to the white matter label a widely distributed microglial population and in addition, cells with light and electron microscopic features of 'gitter cells' that may be involved in the elimination of transitory axons.

TL;DR: In a Golgi study on Wistar rats that were prenatally exposed to alcohol the spine distribution in proximal apical dendrites of layer V pyramidal cells of the parietal cortex was examined, and abnormal dendritic patterns show a striking resemblance to those described by Purpura in mentally retarded children of normal karyotype.

TL;DR: Analysis of [3H]moxestrol uptake by radioautography and by cell nuclear isolation and counting of radioactivity revealed a marked increase in the number of estrogen receptors and estrophilic cells in the brain during late fetal and early postnatal development.

TL;DR: The different sensitivity of systemic KA to induce limbic seizures in neonatal rats may be related to the immaturity of pre- and post-synaptic glutamergic receptors in the hippocampus, which accounts for the preferential activation of the cortex versus hippocampus during the first period of life.

TL;DR: The findings imply that while cells at the periphery are younger on the average, those cells which have become postmitotic at an early stage are not confined to a small central core of the fully developed retina, because the tissue continues to grow and produce postmitsotic cells in all regions of the retina up to day 7.

TL;DR: The objective of the present study was to determine the earliest developmental stage at which vimentin could be detected in the mouse neural tube, and identifies the temporal relationship between the appearance of vimentsin and neural tube development.

TL;DR: Two aspects of this study support the hypothesis that later developing motor patterns will have a greater chance for survival and subsequent development than those which are present at birth, but the hypothesis is not supported when the long-term effect of spinal cord lesions on the maturation of motor behavior is considered.

TL;DR: The postnatal development of some neurotransmitter parameters was measured in lateral geniculate body, superior colliculus and visual cortex of the rat and the possible glial influence on the uptake during development is discussed.

TL;DR: It is indicated that in serum-free aggregating cell cultures of fetal rat telencephalon EGF partially inhibits DNA synthesis, and stimulates an early step in glial differentiation.

TL;DR: Autoradiographic examinations and the determination of the IC50s for GABA uptake inhibitors consistently indicated that the GABA transport system present in stellate astrocytes did not have the features generally attributed to a glial transport system.