O
Osama M. Al-Agha
Researcher at Vancouver General Hospital
Publications - 5
Citations - 1858
Osama M. Al-Agha is an academic researcher from Vancouver General Hospital. The author has contributed to research in topics: Atypical Endometriosis & Cancer. The author has an hindex of 4, co-authored 4 publications receiving 1663 citations. Previous affiliations of Osama M. Al-Agha include University of British Columbia.
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Journal ArticleDOI
ARID1A mutations in endometriosis-associated ovarian carcinomas.
Kimberly C. Wiegand,Sohrab P. Shah,Osama M. Al-Agha,Yongjun Zhao,Kane Tse,Thomas Zeng,Janine Senz,Melissa K. McConechy,Michael S. Anglesio,Steve E. Kalloger,Winnie Yang,Alireza Heravi-Moussavi,Ryan Giuliany,Christine Chow,John Fee,Abdalnasser Zayed,Leah M Prentice,Nataliya Melnyk,Gulisa Turashvili,Allen Delaney,Jason Madore,Stephen Yip,Andrew McPherson,Gavin Ha,Lynda Bell,Sian Fereday,Angela Tam,Laura Galletta,Patricia N. Tonin,Diane Provencher,Dianne Miller,Steven J.M. Jones,Richard A. Moore,Gregg B. Morin,Gregg B. Morin,Arusha Oloumi,Niki Boyd,Samuel Aparicio,Ie Ming Shih,Anne Marie Mes-Masson,David D.L. Bowtell,David D.L. Bowtell,Martin Hirst,Blake Gilks,Marco A. Marra,Marco A. Marra,David G. Huntsman +46 more
TL;DR: These data implicate ARID1A as a tumor-suppressor gene frequently disrupted in ovarian clear-cell and endometrioid carcinomas.
Journal ArticleDOI
Loss of BAF250a (ARID1A) is frequent in high-grade endometrial carcinomas.
Kimberly C. Wiegand,Anna F. Lee,Anna F. Lee,Osama M. Al-Agha,Christine Chow,Steve E. Kalloger,David W. Scott,Christian Steidl,Sam M. Wiseman,Sam M. Wiseman,Randy D. Gascoyne,Blake Gilks,Blake Gilks,David G. Huntsman,David G. Huntsman +14 more
TL;DR: Since BAF250a loss is seen in endometrial carcinomas at a rate similar to that seen in ovarian carcinomas of clear cell and endometrioid type, and is uncommon in other malignancies, it is concluded that loss of BAF 250a is a particular feature of carcinomas arising fromendometrial glandular epithelium.
Journal ArticleDOI
FOXL2 is a sensitive and specific marker for sex cord-stromal tumors of the ovary.
Osama M. Al-Agha,Hassan Huwait,Christine Chow,Winnie Yang,Janine Senz,Steve E. Kalloger,David G. Huntsman,Robert H. Young,C. Blake Gilks +8 more
TL;DR: FoxL2 is a relatively sensitive and highly specific marker for SCST, and staining is present in almost all SCSTs with a FOXL2 mutation, and also in a majority ofSCSTs without a mutation, which forms an immunomarker panel that will result in positive staining with 1 or more markers in essentially all cases of SCST.
Journal ArticleDOI
High-Grade Serous Carcinoma Involving Fallopian Tube, Ovary and Peritoneum.
Osama M. Al-Agha,C. Blake Gilks +1 more
TL;DR: The key features of pelvic SC, current concepts of its pathogenesis, histopathological diagnostic criteria, discuss differential diagnosis, and review diagnostic ancillary studies that can be used in practice are reviewed.
Journal ArticleDOI
Clinical Conundrum: A Case of Cervical Giant Condyloma Acuminatum.
TL;DR: In this article , a 35-year-old woman presented with abnormal uterine bleeding and a suspicious cervical mass, and a diagnostic loop electrical excision procedure identified a giant condyloma acuminatum.