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Showing papers in "Surgical Pathology Clinics in 2011"


Journal ArticleDOI
TL;DR: An overview of various odontogenic cysts and tumors, with microsopic features, gross features, differential diagnosis, prognosis, and potential diagnostic pitfalls are provided.

223 citations


Journal ArticleDOI
TL;DR: A guide for pathologic evaluation of PDAC specimens with the macroscopic and microscopic features of common PDAC and its variants is provided and the differential diagnosis and morphologic and immunophenotypical prognostic parameters are discussed.

84 citations


Journal ArticleDOI
TL;DR: This article presents an overview of the diagnostic categories of benign and malignant nerve sheath tumors, including neuroma, neurofibroma, nerve she Heath myxoma, perineurioma, schwannoma, andmalignant peripheral nerveSheath tumor.

41 citations


Journal ArticleDOI
TL;DR: Information is presented on the pathology of spindle cell sarcomas in terms of an overview of the tumor, microscopic and gross features, diagnostic techniques, genetic markers, differential diagnosis, clinical details, and prognosis.

20 citations


Journal ArticleDOI
TL;DR: Benign tumors, although histologically less diverse, are far more common, with pleomorphic adenoma and Warthin tumor the most common salivary gland tumors.

17 citations


Journal ArticleDOI
Susan Muller1
TL;DR: Proliferative verrucous leukoplakia, an unusual clinical disease, mimics oral lichen planus clinically and requires careful correlation of the clinical and pathologic features.

15 citations


Journal ArticleDOI
TL;DR: This review describes the clinicopathologic characteristics, differential diagnosis, and biologic behavior of exocrine pancreatic tumors of predominantly nonductal differentiation: acinar cell carcinoma, pancreatoblastoma, and solid-pseudopapillary neoplasm.

14 citations


Journal ArticleDOI
TL;DR: Variants of oral and oropharyngeal SCC are discussed and those features that help distinguish human papillomavirus-related from human papillsomav virus-unrelated S CC are highlighted.

14 citations


Journal ArticleDOI
TL;DR: Pancreatic intraepithelial neoplasias are the most common of the pancreatic cancer precursor lesions, yet they remain poorly understood and are so small that they are almost clinically undetectable.

14 citations


Journal ArticleDOI
TL;DR: Immunohistochemical stains for p53, p16, ER, PR, mib-1, hepatocyte nuclear factor 1β and pan-cytokeratin can be helpful in classifying high-grade carcinomas but should be used in concert with thorough morphologic examination, as part of a rational panel of markers and only in specific circumstances.

13 citations


Journal ArticleDOI
TL;DR: The molecular pathogenesis of certain tumors, such as mucoepidermoid carcinoma and adenoid cystic carcinoma, has recently begun to be elucidated.

Journal ArticleDOI
TL;DR: This review presents a discussion of the gross and microscopic features, diagnosis, differential diagnosis, and prognosis of neoplastic lesions of the cervix.

Journal ArticleDOI
TL;DR: In this review, ovarian metastatic carcinomas from various sites, as well as other neoplasms secondarily involving the ovary, are discussed and the value of immunohistochemistry in distinguishing between primary and metastatic neoplasm in the Ovary is discussed.

Journal ArticleDOI
TL;DR: The authors address a group of loosely associated, characteristically benign soft tissue neoplasms that exhibit partial myoid differentiation and attempt to clarify the distinct architectural patterns and the corresponding immunophenotypic and ultrastructural features that distinguish myofibroma, myopericytoma, myoepithelioma, and my ofibroblastoma.

Journal ArticleDOI
TL;DR: This review addresses typical and atypical pathologic features of Pan-NETs, with a focus on practical issues involved in differential diagnosis, immunohistochemical work-up, intraoperative frozen section interpretation, sources of diagnostic errors, and classification.

Journal ArticleDOI
TL;DR: This review covers the group of relatively uncommon nonserous ovarian epithelial tumors, focusing on the group's distinctiveness from the much more common serous tumors and showing the similarities across entities.

Journal ArticleDOI
TL;DR: Evidence-based histologic criteria for atypical endometrial hyperplasia and low grade endometrian carcinoma (both FIGO grade 1 and 2) are presented with emphasis on common and not so common histologic mimics.

Journal ArticleDOI
TL;DR: As tumors with primitive round cell morphology are seen in virtually every basic tumor category, the diagnosis of small round cell neoplasms requires the use of ancillary diagnostic techniques: immunohistochemistry and often molecular genetics.

Journal ArticleDOI
TL;DR: The most commonly encountered pancreatic lesions and the importance of correlation of cytologic features with clinical, radiologic, and ancillary studies for accurate diagnosis are focused on.

Journal ArticleDOI
TL;DR: This article presents an overview of soft tissue tumors that have a plexiform histomorphology, including the more commonly encountered entities, and information on clinical features, microscopic findings, ancillary studies, differential diagnosis, and prognosis is provided.

Journal ArticleDOI
TL;DR: The sinonasal tract (SNT) includes the nasal cavity and paranasal sinuses and may give rise to a variety of nonneoplastic and neoplastic proliferations, including benign and malignant neoplasms.

Journal ArticleDOI
TL;DR: Metastatic clear cell tumors, including renal cell carcinoma and adrenal cortical carcinoma, should be considered in the differential diagnosis and excluded through clinical history, imaging studies, and immunohistochemical stains.

Journal ArticleDOI
TL;DR: The key features of pelvic SC, current concepts of its pathogenesis, histopathological diagnostic criteria, discuss differential diagnosis, and review diagnostic ancillary studies that can be used in practice are reviewed.

Journal ArticleDOI
TL;DR: Carcinoma of the vulva is an uncommon malignant neoplasm and represents 4% of all genital cancers in women, and squamous cell carcinoma is the most common histologic type.

Journal ArticleDOI
TL;DR: Characteristics of disorders such as chronic, autoimmune, eosinophilic, hereditary, and infectious pancreatitis are described to convey an appreciation of these disorders because their recognition can benefit patients tremendously, as inflammatory lesions of the pancreas can be mass-forming, giving rise to pseudotumors, and leading to surgical resection that may otherwise be unnecessary.

Journal ArticleDOI
TL;DR: The clinical, radiographic, and pathologic features of tumors and tumorlike lesions affecting the bones of the head and neck region, particularly those that occur with more frequency or those that are unique to this part of the skeleton are described.

Journal ArticleDOI
TL;DR: The authors present an overview of the disease and discussions of genetic predisposition, prevention, screening, and diagnosis of ovarian, fallopian tube and primary peritoneal carcinomas as well as surgical and chemotherapeutic techniques for the various stages of disease.

Journal ArticleDOI
TL;DR: This content presents a review of molecular pathology of ovarian cancer, and presents key molecular features for high-grade and low-grade serous carcinomas, endometrioid carcinomes, clear cell carcinoma, and mucinous carcinomas.

Journal ArticleDOI
TL;DR: The clinicopathologic characteristics and differential features of pancreatic mucinous tumors are presented, which appear important to distinguish them from other cystic neoplasms and non-neoplastic cysts.

Journal ArticleDOI
TL;DR: This review focuses on recent advances in the area ofLow-grade ovarian serous neoplasia with emphasis on key diagnostic criteria, differential diagnosis, and disease classification based on current understanding of low-grade serous carcinogenesis.