P. Davis

TL;DR: The use of theoretically calculated molecular properties as predictors for retention in reversed-phase HPLC has been explored in this paper, where a subset of the experimental data (a training set) was used to derive property-retention time relationships and the remaining data were then used to test the predictive capability of the methods.

TL;DR: The dual nature of the retention mechanism allowed the retention of ionisable molecules to be adjusted using pH whilst that of uncharged compounds was unaffected.

TL;DR: The micellar capillary electrophoresis technique was found to be suitable for the analysis of purified ecdysteroid-rich extracts of plants and the eggs of the desert locust and the elution order of the analytes was similar to that obtained using reversed-phase HPLC.

TL;DR: Over the last decade high performance liquid chromatography has become firmly established as the pre-eminent separation technique for the chromatography and analysis of drugs and pharmaceuticals and the adoption of new techniques such as SFC must be considered.