P. De Los Rios

TL;DR: A new mechanism leading to scale-free networks is proposed, which is called a good-get-richer mechanism, in which sites with larger fitness are more likely to become hubs (i.e., to be highly connected).

TL;DR: The network-based approach allows for the analysis of the thermodynamics and kinetics of biomolecule isomerization without reliance on arbitrarily chosen order parameters and it is shown on low-dimensional models, that the broad-tailed weight distribution observed in their networks originates from free-energy basins with mainly enthalpic character.

TL;DR: Experimental evidence is shown that the aggregation and collapse of an amphiphilic polymer, poly-N-isopropyl acrylamide (PNiPAM), in aqueous solutions containing small amounts of alcohol finds that the thermodynamic characteristics defining the phase transitions of PNiPAM evolve relative to the solvent composition at which the excess mixing enthalpy of the water/alcohol mixtures becomes minimal.

TL;DR: It is shown that spontaneous localization of energy occurs generically and is a site-dependent process, suggesting that nonlinear phenomena may play an important role in enzyme function, allowing for energy storage during the catalytic process.

TL;DR: These experiments provide a basis for the functional study of protein microdomains and also suggest opportunities for sensitive screening of drugs that can modulate protein–protein interactions.