P
P.F. Fellows
Researcher at United States Army Medical Research Institute of Infectious Diseases
Publications - 19
Citations - 1800
P.F. Fellows is an academic researcher from United States Army Medical Research Institute of Infectious Diseases. The author has contributed to research in topics: Bacillus anthracis & Anthrax vaccines. The author has an hindex of 16, co-authored 19 publications receiving 1764 citations.
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Journal ArticleDOI
In vitro correlate of immunity in a rabbit model of inhalational anthrax.
Margaret L. Pitt,Stephen F. Little,Bruce E. Ivins,P.F. Fellows,J. Barth,John Hewetson,Paul H. Gibbs,Mark T. Dertzbaugh,Arthur M. Friedlander +8 more
TL;DR: A serological correlate of vaccine-induced immunity was identified in the rabbit model of inhalational anthrax and antibody levels to PA at both 6 and 10 weeks were significant predictors of survival.
Journal ArticleDOI
Comparative efficacy of experimental anthrax vaccine candidates against inhalation anthrax in rhesus macaques.
Bruce E. Ivins,Margaret L. Pitt,P.F. Fellows,Joseph Farchaus,G. E. Benner,David M. Waag,Stephen F. Little,G.W. Anderson,Paul H. Gibbs,Arthur M. Friedlander +9 more
TL;DR: The authors examined the efficacy of Bacillus anthracis protective antigen (PA) combined with adjuvants as vaccines against an aerosol challenge of virulent anthrax spores in rhesus macaques.
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Passive protection by polyclonal antibodies against Bacillus anthracis infection in guinea pigs.
TL;DR: It is demonstrated that antibodies produced against only PA can provide passive protection against anthrax infection in guinea pigs.
Journal ArticleDOI
Efficacy of a human anthrax vaccine in guinea pigs, rabbits, and rhesus macaques against challenge by Bacillus anthracis isolates of diverse geographical origin
P.F. Fellows,M.K. Linscott,Bruce E. Ivins,Margaret L. Pitt,Cynthia A. Rossi,Paul H. Gibbs,Arthur M. Friedlander +6 more
TL;DR: It is demonstrated that, although AVA confers variable protection against different B. anthracis isolates in guinea pigs, it is highly protective against these same isolate in both rabbits and rhesus macaques.
Journal ArticleDOI
Defining a serological correlate of protection in rabbits for a recombinant anthrax vaccine.
Stephen F. Little,Bruce E. Ivins,P.F. Fellows,Margaret L. Pitt,Sarah L. Norris,Gerard P. Andrews +5 more
TL;DR: Results suggested that the antibody response, as determined by the quantitative anti-rPA IgG ELISA and toxin neutralizing antibody (TNA) assay, were significant predictors of protection against a B. anthracis aerosol spore challenge in rabbits.