P. Gehron Robey

TL;DR: It is demonstrated that DPSCs possess stem-cell-like qualities, including self-renewal capability and multi-lineage differentiation, including single-colony-derived DPSC strains that differ from each other with respect to their rate of odontogenesis.

TL;DR: Enzyme-linked immunoadsorbant assays have been developed for types I, II, III, and IV collagen and for laminin and fibronectin and offer a specific, sensitive, and convenient method for the measurement of various connective tissue components either separately or simultaneously.

TL;DR: It is reported that bgn deficiency leads to structural abnormality in collagen fibrils in bone, dermis, and tendon, and to a “subclinical” cutaneous phenotype with thinning of the dermis but without overt skin fragility.

TL;DR: This study provided direct evidence to suggest that osteogenesis and dentinogenesis mediated by BMSSCs and DPSCs, respectively, may be regulated by distinct mechanisms, leading to the different organization of the mineralized and non-mineralized tissues.

TL;DR: The finding that bone marrow stromal cells can be manipulated in vitro and subsequently form bone in vivo provides a powerful new model system for studying the basic biology of bone and for generating models for therapeutic strategies aimed at regenerating skeletal elements.