P. Kannouche

TL;DR: The data indicate that the signal flow induced by UV radiation addresses not only protein stability and transcription but also RNA stability, a hitherto-unrecognized level of UV-induced regulation.

TL;DR: (Mm)Kin17 overexpression reduced the proliferation of tumorigenic cells independently of their p53 status and modified cell growth and cell morphology of established HEK 293 cells producing (Mm]Kin17 protein.

TL;DR: The results indicate that the cross-reactivity with the anti-RecA antibodies is due to an antigenic determinant located in the core of kin17 protein, between residues 129 and 228, and it is hypothesised that these dot-like structures reflect nuclear metabolism compartmentalization.

TL;DR: The cloning of the mouse Kin-17 cDNA is summarized and work on the identification and preliminary characterisation of the biochemical properties of mouse kin17 protein, a new nuclear protein able to recognize bent DNA and suspected to be involved in illegitimate recombination is discussed.

TL;DR: The cross-hybridization of Kin17 cDNA with the genomic DNA of other species in Southern analysis indicates the conservation of the gene among mammals and suggests that the Kin17 gene plays a conserved role in DNA metabolism.