J. Appl. Cryst.の発刊に際して

10. Patented Literature 2616 10.1. Esterification 2616 10.2. Ether Formation 2619 10.2.1. Etherification without Cyclization 2619 10.2.2. Etherification with Cyclization 2624 10.3. N-Alkylation 2625 10.4. Other Reactions 2627 11. Summary and Outlook 2628 12. Note Added in Proof 2628 13. Abbreviations Used in This Review 2629 14. Acknowledgments 2629 15. Supporting Information Available 2630 16. References 2630

Mitsunobu and Related Reactions: Advances and Applications

The Complementary Competitors: Palladium and Copper in C-N Cross-Coupling Reactions

Green synthesis of silver nanoparticles using Alternanthera dentata leaf extract at room temperature and their antimicrobial activity

Cover -- Advancesin Heterocyclic Chemistry13; -- Copyright Page -- Contents -- Contributors -- Preface13; -- Chapter 113; Hexameric Macrocyclic Architectures in Heterocyclic Chemistry -- 1. Introduction -- 2. Macrocycles with Five-Membered Heterocyclic Subunits -- 3. Six-Membered Ring Heterocycles -- 4. Miscellaneous Heterocyclic Materials -- 5. Conclusions -- References -- Chapter 2 13;Metal-Catalyzed Intramolecular Heteroatom (X)!Carbon(C) Functional Group Migration Reactions Involving Additionsof X2;Y Bonds Across Alkynes -- 1. Introduction -- 2. Synthesis of O-Containing Heterocycles -- 3. Synthesis of N-Containing Heterocycles -- 4. Synthesis of S-Containing Heterocycles -- 5. Synthesis of Se-Containing Heterocycles -- 6. Conclusions -- Acknowledgments -- References -- Chapter 313; Biindolyls -- 1. Introduction -- 2. Synthesis -- 3. Reactions -- 4. Conclusion -- References -- Chapter 413; The Annulation of 2-Imidazolines -- 1. Introduction -- 2. Polar Annulation Strategy -- 3. Imidazolines as Double Nucleophiles -- 4. Annulations of the Enamino Ester/Ketene Aminal -- 5. Annulations of N-Unsubstituted 2-Imidazolines -- 6. Imidazolines as Sources of 1,3-Dipoles -- 7. Azomethine Ylides by Alkylation2;Deprotonation -- 8. Azomethine Ylides by Carbene Insertion in a Catalytic Cycle -- 9. Azomethine Ylides by Conjugate Addition-Proton Transfer -- 10. Annulations Using Chiral Imidazolines -- 11. Optically Active Piperidines via Enamino Ester Annulation -- 12. Dipolar Cycloaddition of Optically Active Imidazolinium Ylides -- 13. Chiral Imidazoline Nitrones in Cycloadditions -- 14. Summary -- References -- Chapter 5 Recent Advances in the Dimroth Rearrangement: A ValuableTool for the Synthesis of Heterocycles -- 1. Introduction -- 2. Translocation of Heteroatoms in Fused Heterocycles (Type 1) -- 3. Translocation of Exo- and Endocyclic Heteroatoms in Heterocycles(Type 2) -- Acknowledgments -- References -- Subject Index.

Advances in Heterocyclic Chemistry

A series of 1H-isochromen-1-one derivatives and their thio analogues were synthesized by thionation using Lawesson's reagent for evaluation of their cytotoxic effect on cancer cells. The effect of these derivatives was tested on the growth of human epidermoid carcinoma A431 cell line by MTT [3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide] colorimetric assay. MTT assay revealed that these new compounds are potent inhibitors of cell growth. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.

Synthesis and Antiproliferative Activity of Some 1H-Isochromen-1-ones and Their Thio Analogues

A new series of 1,2,3-selenadiazoles containing an aryl or a 3-arylisoquinoline sulfanyl moiety at carbons 4 and 5, respectively, was prepared by cyclization of the respective semicarbazones in the presence of selenium(II) oxide and tetrahydrofuran at 70–75°C. Semicarbazones required for the reaction were obtained from 2-((3-arylisoquinolin-1-yl)sulfanyl)-1-phenylethanones, I, by a reaction with semicarbazide hydrochloride in ethanol/water mixture and potassium acetate base.

Facile synthesis of 3-aryl-1-((4-aryl-1,2,3-selenadiazol-5-yl)sulfanyl)isoquinolines

Iron-oxide nanoparticles were obtained using chitosan templates and their crystalline character and particle size have been confirmed through powder x-ray diffraction and transmission electron microscopy measurements. The particle sizes were found to be 10–25 nm. The diversified chalcones 2 were reacted with 1-hydrazinylisoquinoline 1 in the presence of iron-oxide nanoparticles to the corresponding pyrazolines 3a–j in high yield and purity. The pyrazolines were characterized by spectroscopic techniques.

Iron-oxide nanoparticles mediated cyclization of 3-(4-chlorophenyl)-1-hydrazinylisoquinoline to 1-(4,5-dihydropyrazol-1-yl)isoquinolines

The asymmetric unit of the title compound, C16H12O3, contains two crystallographically independent mol­ecules. The isochromene ring system is planar (maximum deviation 0.024 A) and is oriented at dihedral angles of 2.63 (3) and 0.79 (3)° with respect to the methoxy­benzene rings in the two independent mol­ecules.

/pdf/3-4-methoxy-phen-yl-1h-isochromen-1-one-mgdsqwyw07.pdf

3-(4-Methoxy-phen-yl)-1H-isochromen-1-one.

An attempt was made to develop potato hybrids with combined resistance to late blight and potato virus Y. Five crosses were made between the late blight resistant (PVY susceptible-nulliplex) and PVY resistant (duplex, late blight susceptible) parents and progenies were screened for both the diseases. The present study reveals that there is ample scope to combine high yield with late blight and PVY resistance in potato.

http://epubs.icar.org.in/ejournal/index.php/PotatoJ/article/download/33062/14652

P. Manivel

Papers

Synthesis and Antiproliferative Activity of Some 1H-Isochromen-1-ones and Their Thio Analogues

Facile synthesis of 3-aryl-1-((4-aryl-1,2,3-selenadiazol-5-yl)sulfanyl)isoquinolines

Iron-oxide nanoparticles mediated cyclization of 3-(4-chlorophenyl)-1-hydrazinylisoquinoline to 1-(4,5-dihydropyrazol-1-yl)isoquinolines

3-(4-Methoxy-phen-yl)-1H-isochromen-1-one.

Combining resistance to late blight and pvy in potato