P
Pablo R. Castillo
Researcher at Mayo Clinic
Publications - 77
Citations - 2717
Pablo R. Castillo is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Population & Pittsburgh Sleep Quality Index. The author has an hindex of 17, co-authored 71 publications receiving 2419 citations. Previous affiliations of Pablo R. Castillo include University of Minnesota & El Bosque University.
Papers
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Journal ArticleDOI
Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease
B. F. Boeve,M. H. Silber,Clifford B. Saper,Tanis J. Ferman,Dennis W. Dickson,Joseph E. Parisi,Eduardo E. Benarroch,J. E. Ahlskog,Glenn E. Smith,R. C. Caselli,M. Tippman-Peikert,E. J. Olson,Siong-Chi Lin,T. Young,Z. Wszolek,C. H. Schenck,M. W. Mahowald,Pablo R. Castillo,K. Del Tredici,Heiko Braak +19 more
TL;DR: The data suggest that many patients with 'idiopathic' RBD are actually exhibiting an early clinical manifestation of an evolving neurodegenerative disorder, and may be appropriate for future drug therapies that affect synuclein pathophysiology, in which the development of parkinsonism and/or dementia could be delayed or prevented.
Journal ArticleDOI
Steroid-Responsive Encephalopathy Associated With Autoimmune Thyroiditis
Pablo R. Castillo,Bryan K. Woodruff,Richard J. Caselli,Steven Vernino,Claudia F. Lucchinetti,Jerry W. Swanson,John H. Noseworthy,Allen J. Aksamit,Jonathan L. Carter,Joseph I Sirven,Gene G. Hunder,Vahab Fatourechi,Bahram Mokri,Daniel A. Drubach,Sean J. Pittock,Vanda A. Lennon,Brad F. Boeve +16 more
TL;DR: Until the pathophysiologic mechanism of this and other autoimmune encephalopathies is better characterized, it is believed that descriptive terms that reflect an association rather than causation are most appropriate for this syndrome.
Journal Article
Worst Headache and Subarachnoid Hemorrhage: Prospective, Modern Computed Tomography and Spinal Fluid Analysis
Lewis B. Morgenstern,Hortencia Luna-Gonzales,John C. Huber,Shan S Wong,Margaret O. Uthman,John H Gurian,Pablo R. Castillo,Sandy G Shaw,Ralph F. Frankowski,James C. Grotta +9 more
TL;DR: Modern CT imaging is sufficient to exclude 97.5% of SAH in patients presenting to the ED with "worst headache" symptoms, and CSF spectrophotometric detection was the most sensitive test for blood.
Journal ArticleDOI
Recombinant Factor VIIa for Rapid Reversal of Warfarin Anticoagulation in Acute Intracranial Hemorrhage
William D. Freeman,Thomas G. Brott,Kevin M. Barrett,Pablo R. Castillo,H. Gordon Deen,Leo F. Czervionke,James F. Meschia +6 more
TL;DR: Intravenous bolus administration of rFVIIa can rapidly lower the international normalized ratio and appears to be safe for patients with warfarin-related ICH.
Journal ArticleDOI
EEG findings in steroid-responsive encephalopathy associated with autoimmune thyroiditis.
TL;DR: The EEG is helpful in evaluating and following patients with steroid-responsive encephalopathy associated with autoimmune thyroiditis in reflecting the degree of central nervous system (CNS) involvement, in determining whether their condition is better or worse, and in ruling out other causes of encephalitis.