D
David Hutton
Researcher at University of Bristol
Publications - 5
Citations - 2080
David Hutton is an academic researcher from University of Bristol. The author has contributed to research in topics: Rate ratio & Randomized controlled trial. The author has an hindex of 3, co-authored 5 publications receiving 1011 citations.
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Journal ArticleDOI
Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results.
Hongchao Pan,Richard Peto,Ana-Maria Henao-Restrepo,Marie-Pierre Preziosi,Vasee Sathiyamoorthy,Quarraisha Abdool Karim,Marissa M. Alejandria,César Hernández García,Marie-Paule Kieny,Reza Malekzadeh,Srinivas Murthy,K. Srinath Reddy,Mirta Roses Periago,Pierre Abi Hanna,Florence Ader,Abdullah M. Al-Bader,Almonther Alhasawi,Emma Allum,Athari Alotaibi,Carlos A Alvarez-Moreno,Sheila Appadoo,Abdullah Asiri,Pål Aukrust,Andreas Barratt-Due,Samir Bellani,Mattia Branca,Heike B. C. Cappel-Porter,Nery Cerrato,Ting S. Chow,Najada Como,Joseph A. Eustace,Patricia J. Garcia,Sheela Godbole,Eduardo Gotuzzo,Laimonas Griskevicius,Rasha Hamra,Mariam Hassan,Mohamed Hassany,David Hutton,Irmansyah Irmansyah,Ligita Jancoriene,Jana Kirwan,Suresh Kumar,Peter Lennon,Gustavo Lopardo,Patrick Lydon,Nicola Magrini,Teresa Maguire,Suzana Manevska,Oriol Manuel,Sibylle McGinty,Marco T. Medina,María L. Mesa Rubio,Maria C. Miranda-Montoya,Jeremy Nel,Estevão Portela Nunes,Markus Perola,Antonio Portolés,Menaldi R. Rasmin,Aun Raza,Helen Rees,Paula P. S. Reges,Chris A Rogers,Kolawole Salami,Marina I. Salvadori,Narvina Sinani,Jonathan A C Sterne,Milena Stevanovikj,Evelina Tacconelli,Kari A.O. Tikkinen,Sven Trelle,Hala Zaid,John-Arne Røttingen,Soumya Swaminathan +73 more
TL;DR: These remdesivir, hydroxychloroquine, lopinavir, and interferon regimens had little or no effect on hospitalized patients with Covid-19, as indicated by overall mortality, initiation of ventilation, and duration of hospital stay.
Journal ArticleDOI
Safety and immunogenicity of concomitant administration of COVID-19 vaccines (ChAdOx1 or BNT162b2) with seasonal influenza vaccines in adults in the UK (ComFluCOV): a multicentre, randomised, controlled, phase 4 trial.
Rajeka Lazarus,Sarah Baos,Heike Cappel-Porter,Andrew Carson-Stevens,Madeleine Clout,Lucy Culliford,Stevan R Emmett,Jonathan Garstang,Lukuman Gbadamoshi,Bassam Hallis,Rosie A Harris,David Hutton,Nick Jacobsen,Katherine Joyce,Rachel Kaminski,Vincenzo Libri,Alex Middleditch,Liz McCullagh,Ed Moran,Adrian Phillipson,Elizabeth Price,John M Ryan,Russell C J Thirard,Rachel Todd,Matthew D. Snape,David Tucker,Rachel Williams,Jonathan S. Nguyen-Van-Tam,Adam Finn,Chris A Rogers,Kirsty Adams,Seema Alaee,Parvinder K. Aley,Emma Allum,Sally Anthony,Kate Ashton,Tanya Awal,Liz Barnett,Alison Barratt,Charlotte Barron,Holly Baum,Chloe Beard,Lorna Bennett,Samuel Bird,Sarah Bishop,Jess Bisset,Pritesh Bodalia,Jane Bowles,Catherine Bowyer,Kirstie Bradburn,Jonathan J.H. Bray,Catherine Bressington,Matthew Brimfield,Lauren Broad,Pauline Brown,Ruth Brydon-Hill,Sharon Burge,David Carmichael,Gurjit Chohan,Tonia Clark,Adrianne Close,Tom Coleman,Claire Cowley,Charlotte Cranfield,Eleanor Cross,Alyssa D'Agostino,Silvia D'Arcangelo,Ashley Otter,Kate Davies,Catrin Davies,Ru Davies,Louisa Davies,Kimberley Driver,Charlotte Eglinton,Charlotte Ekblad,Emma Eldridge,Teriann Evans,Mim Evans,Isabel Evans,Yama F Mujadidi,Amanda Farrow,Beverley Faulkner,Sally Feltham,Susan Figueirido,Jamie Ford,David Foxwell,Sharon Frayling,Sophie Gardiner,Karen E. Gooch,Jayne Goodwin,Alice Halliday,Shama Hamal,Sarah Harrhy,Andrew Harris,Lesley Haxton,Matthew Haynes,Mae Hazell,Tracey Hembrough,Jacqueline Hewson,Bethany Hicks,T. Twistington Higgins,Michelle Hill,Alex Hills,Zoe Hilton,Benjamin Hitchings,Cheryl Hua,Hina Iftikhar,Attya Iqbal,Laura Jones,Nicola Jones,Johanna K Kellett Wright,Sarah Kidd,Alison Kirby,Lucy Knibbs,Jenny Lamb,Helen Langton,Rwth Leach,Phoebe Lewis-Clarke,Amy Lloyd,Kirsty Maclean,Nicola Manning,Anthony Marriott,Isobel Joy McFadzean,Maeve McLaughlin,Alison McQueen,Bianca Mills,Gurudutt Naik,Lisa Nicholls,Chris Norman,Keren Northcott,Kerry Nyland,Catherine Oliver,Elizabeth Oliver,Jennifer Oliver,Diana Owen,Jemma Paterson,Lauren Pearce,Suzannah Pegler,Zoe Price,William B. Pynsent,Lidia Ramos,Tommy Rampling,David Rea,Karen Regan,Tawassal Riaz,Marivic Ricamara,Danielle Rice,Melody Rich,Marianne Roots,Kathryn Ann Ryan,Yukari Sakagami,Ahmed Salem,Jade Salter-Hewitt,Michelle Samuels,Silvia Santoloce,Siwan Seaman,Michael Seneviratne,Sara Shankland,Louise Silva,Katie Smart,Rachel M. Smith,Joyce Smith,Rebecca Stringer,Helen Talbot,Teresa Tarling,Sarah Louise Taylor,Amy Hughes Thomas,Grace Tilzey,Gina Townley,Lisa Trembath,Kate Turkentine,Kelly Turner,Jenny Tyler,Jacinta Ugoji,Katharine Wale,Terrie Walker-Smith,Maggie Walton,Barbara Warnes,Sarah Whittley,Jennie Williams,Gail M. Williams,Kevin Williamson,Yee Ting Nicole Yim,Nicola Youlden +183 more
TL;DR: In this article, the safety of concomitant vaccination with COVID-19 and influenza vaccines was evaluated in a randomized, controlled, phase 4 trial, where participants were randomly assigned to receive either an age-appropriate influenza vaccine or placebo alongside their second dose of COVID19 vaccine.
Journal ArticleDOI
Screening for hereditary haemochromatosis within families and beyond.
TL;DR: Overall efficacy of population screening for haemochromatosis is undermined by observations that a substantial number of untested relatives had undiagnosed iron overload.
Journal ArticleDOI
Development of the "GeneSYS" database system to support trial data capture and conduct
TL;DR: Recognising the need to develop flexible database solutions quickly, and that are easily maintained throughout the life cycle of a study, the CTU database development team conceived and developed the “GeneSYS” database solution.
Journal ArticleDOI
Improving the efficiency of testing database functionality through statistical involvement
TL;DR: This work describes how, with statistical involvement, the testing has been streamlined and the timelines reduced in customised databases to collect and store study data and manage clinical trials.