P
Panayiotis Nikolaou
Researcher at Vanderbilt University
Publications - 32
Citations - 1096
Panayiotis Nikolaou is an academic researcher from Vanderbilt University. The author has contributed to research in topics: Hyperpolarization (physics) & Xenon. The author has an hindex of 14, co-authored 31 publications receiving 889 citations. Previous affiliations of Panayiotis Nikolaou include Vanderbilt University Medical Center & Southern Illinois University Carbondale.
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Journal ArticleDOI
NMR Hyperpolarization Techniques for Biomedicine
TL;DR: This article explores selected advances in methods for the preparation and use of hyperpolarized contrast agents, many of which are already at or near the phase of their clinical validation in patients.
Journal ArticleDOI
Near-unity nuclear polarization with an open-source 129Xe hyperpolarizer for NMR and MRI
Panayiotis Nikolaou,Aaron M. Coffey,Laura L. Walkup,Brogan M. Gust,Nicholas Whiting,Hayley Newton,Scott Barcus,Scott Barcus,Iga Muradyan,Mikayel Dabaghyan,Gregory D. Moroz,Matthew S. Rosen,Samuel Patz,Michael J. Barlow,Eduard Y. Chekmenev,Boyd M. Goodson +15 more
TL;DR: A unique low-cost “open-source” xenon “hyperpolarizer” is described, its ability to produce xenon-129 with high magnetization is characterized, its utility for human lung imaging is demonstrated, and excellent agreement is observed among four independent methods used to measure spin polarization.
Journal ArticleDOI
NMR Hyperpolarization Techniques of Gases.
Danila A. Barskiy,Aaron M. Coffey,Panayiotis Nikolaou,Dmitry M. Mikhaylov,Boyd M. Goodson,Rosa T. Branca,George J. Lu,Mikhail G. Shapiro,Ville-Veikko Telkki,Vladimir V. Zhivonitko,Igor V. Koptyug,Oleg G. Salnikov,Kirill V. Kovtunov,Valerii I. Bukhtiyarov,Matthew S. Rosen,Michael J. Barlow,Shahideh Safavi,Ian P. Hall,Leif Schröder,Eduard Y. Chekmenev,Eduard Y. Chekmenev +20 more
TL;DR: This Minireview covers the fundamentals of the preparation of hyperpolarized gases and focuses on selected applications of interest to biomedicine and materials science.
Journal ArticleDOI
A 3D-printed high power nuclear spin polarizer.
Panayiotis Nikolaou,Aaron M. Coffey,Laura L. Walkup,Brogan M. Gust,Cristen LaPierre,Edward Koehnemann,Michael J. Barlow,Matthew S. Rosen,Boyd M. Goodson,Eduard Y. Chekmenev +9 more
TL;DR: The utility of this SEOP setup is demonstrated here to obtain near-unity (129)Xe polarization values in a 0.5 L optical pumping cell, including ∼74 ± 7% at 1000 Torr xenon partial pressure, a record value at such high Xe density.
Journal ArticleDOI
XeNA: An automated ‘open-source’ 129Xe hyperpolarizer for clinical use
Panayiotis Nikolaou,Panayiotis Nikolaou,Aaron M. Coffey,Laura L. Walkup,Brogan M. Gust,Nicholas Whiting,Hayley Newton,Iga Muradyan,Mikayel Dabaghyan,Kaili Ranta,Gregory D. Moroz,Matthew S. Rosen,Samuel Patz,Michael J. Barlow,Eduard Y. Chekmenev,Boyd M. Goodson +15 more
TL;DR: The primary focus of this paper is on the technical/engineering development of the polarizer, with the explicit goals of facilitating the adaptation of design features and operative modes into other laboratories, and of spurring the further advancement of HP-gas MR applications in biomedicine.