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Paola Milla
Researcher at University of Turin
Publications - 66
Citations - 1578
Paola Milla is an academic researcher from University of Turin. The author has contributed to research in topics: Cyclase & Active site. The author has an hindex of 17, co-authored 62 publications receiving 1364 citations.
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Journal ArticleDOI
PEGylation of proteins and liposomes: a powerful and flexible strategy to improve the drug delivery.
TL;DR: The principles of PEGylation chemistry are elucidated and some enlightening examples of how this technology could dramatically influence the clinical application of therapeutic biomolecules are focused on.
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Systematic analysis of yeast strains with possible defects in lipid metabolism.
Günther Daum,Gabriele Tuller,Tamara Nemec,Cladia Hrastnik,Gianni Balliano,Luigi Cattel,Paola Milla,Flavio Rocco,Aadreas Conzelmann,Christine Vionnet,Diane E. Kelly,Steven L. Kelly,Eckhard Schweizer,Hans-Joachim Schüller,Ursula Hojad,Eva Greiner,Kerin Finger +16 more
TL;DR: A group of five European laboratories established methods suitable to screen for novel genes of the yeast Saccharomyces cerevisiae involved in lipid metabolism, regulation of lipid biosynthesis and the role of lipids in organellar membranes, and found evidence suggesting a possible role in cholesterol metabolism.
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Hyaluronic Acid Conjugates as Vectors for the Active Targeting of Drugs, Genes and Nanocomposites in Cancer Treatment
TL;DR: This review describes recent progress made with the several chemical strategies adopted to synthesize conjugates and prepare novel delivery systems with improved behaviors.
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Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles.
Paola Milla,Karin Athenstaedt,Franca Viola,Simonetta Oliaro-Bosso,Sepp D. Kohlwein,Guenther Daum,Gianni Balliano +6 more
TL;DR: In this article, Xenstaedt et al. showed that Erg7p is almost exclusively associated with this compartment as shown by analysis of enzymatic activity, Western blot analysis, and in vivo localization of erg7p-GFP.
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Administration of reduced glutathione in FOLFOX4 adjuvant treatment for colorectal cancer: effect on oxaliplatin pharmacokinetics, Pt-DNA adduct formation, and neurotoxicity.
TL;DR: It is indicated that coadministration of GSH is an effective strategy to reduce the oxaliplatin-induced neurotoxicity without impairing neither the pharmacokinetics of oxali Platin, nor the Pt-DNA adduct formation.