P
Partha Ghosh
Researcher at Central University of Jharkhand
Publications - 24
Citations - 363
Partha Ghosh is an academic researcher from Central University of Jharkhand. The author has contributed to research in topics: Catalysis & Acylation. The author has an hindex of 11, co-authored 24 publications receiving 321 citations. Previous affiliations of Partha Ghosh include University of North Carolina at Chapel Hill & University of Kansas.
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Journal ArticleDOI
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy
Kevin J. Frankowski,Michael P Hedrick,Palak Gosalia,Kelin Li,Shenghua Shi,David A Whipple,Partha Ghosh,Thomas E. Prisinzano,Frank J. Schoenen,Ying Su,S Vasile,Eduard Sergienko,Wilson Gray,Santosh Hariharan,Loribelle Milan,Susanne Heynen-Genel,Arianna Mangravita-Novo,Michael Vicchiarelli,Layton H. Smith,John M. Streicher,Marc G. Caron,Larry S. Barak,Laura M. Bohn,Thomas D.Y. Chung,Jeffrey Aubé +24 more
TL;DR: The outcome of a high throughput screening (HTS) campaign-based strategy for the rapid identification and optimization of selective and general chemotypes for both kappa (κ) opioid receptor (KOR) activation and inhibition is presented.
Journal ArticleDOI
Gold‐Catalyzed Oxidative Alkyne Functionalization by N−O/S−O/C−O Bond Oxidants
Journal ArticleDOI
Peptide ligation catalyzed by functionalized gold nanoparticles.
Yannick A Fillon,Ayush Verma,Partha Ghosh,Dawn Ernenwein,Vincent M. Rotello,Jean Chmielewski +5 more
TL;DR: This system displays the use of organically tailored nanoparticles as effective supramolecular reagents for catalyzing bond-forming reactions and may also serve as a model for prebiotic conditions where charged surfaces may have promoted the polymerization of the early biopolymers.
Journal ArticleDOI
Spirodiepoxide reaction with cuprates.
TL;DR: The first example of transition-metal-mediated transformations of spirodiepoxides and the first general method for carbon−carbon bond formation using the spirodiespoxide functional group are reported on.
Journal ArticleDOI
Silyl-substituted spirodiepoxides: stereoselective formation and regioselective opening.
TL;DR: A short synthesis of the natural product epi-citreodiol and the method developed to gain access to this target are described, with key advances focus on silyl substituted allenes.