P
Pascal Dollé
Researcher at French Institute of Health and Medical Research
Publications - 169
Citations - 26799
Pascal Dollé is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Retinoic acid & Retinoic acid receptor. The author has an hindex of 82, co-authored 167 publications receiving 25579 citations. Previous affiliations of Pascal Dollé include University of Strasbourg & Paris Descartes University.
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Journal ArticleDOI
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene.
Hans W. D. Matthes,Rafael Maldonado,Frédéric Simonin,Olga Valverde,Susan Slowe,Ian Kitchen,Katia Befort,Andrée Dierich,Marianne Le Meur,Pascal Dollé,Eleni T. Tzavara,Jacques Hanoune,Bernard P. Roques,Brigitte L. Kieffer +13 more
TL;DR: Investigation of the behavioural effects of morphine reveals that a lack of μ receptors abolishes the analgesic effect of morphine, as well as place-preference activity and physical dependence, and concludes that the µ-opioid-receptor gene product is a mandatory component of the opioid system for morphine action.
Journal ArticleDOI
Embryonic retinoic acid synthesis is essential for early mouse post-implantation development.
TL;DR: It is established that RA synthesized by the post-implantation mammalian embryo is an essential developmental hormone whose lack leads to early embryo death.
Journal ArticleDOI
Retinoic acid signalling during development
Muriel Rhinn,Pascal Dollé +1 more
TL;DR: An overview of the RA biosynthesis, degradation and signalling pathways is provided and the main functions of this molecule during embryogenesis are reviewed.
Journal ArticleDOI
Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants
David Lohnes,Manuel Mark,Cathy Mendelsohn,Pascal Dollé,Andrée Dierich,Philippe Gorry,Anne Gansmuller,Pierre Chambon +7 more
TL;DR: Multiple eye abnormalities are described which are found in various RAR double mutant fetuses and are similar to those previously seen in VAD fetuses, and further abnormalities not previously reported in Vad fetuses are found.
I) Craniofacial and skeletal abnormalities in RAR double mutants
David Lohnes,Manuel Mark,Cathy Mendelsohn,Pascal Dollé,Andrée Dierich,Philippe Gorry,Anne Gansmuller,Pierre Chambon +7 more
TL;DR: The role of retinoic acid and of the RARs in the onto genesis of the affected structures, particularly of those that are derived from mesenchymal neural crest cells, is discussed in this article.