P
Pascal Dollé
Researcher at French Institute of Health and Medical Research
Publications - 169
Citations - 26799
Pascal Dollé is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Retinoic acid & Retinoic acid receptor. The author has an hindex of 82, co-authored 167 publications receiving 25579 citations. Previous affiliations of Pascal Dollé include University of Strasbourg & Paris Descartes University.
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Transcriptomic analysis of murine embryos lacking endogenous retinoic acid signaling.
Marie Paschaki,Carole Schneider,Muriel Rhinn,Christelle Thibault-Carpentier,Doulaye Dembélé,Karen Niederreither,Pascal Dollé +6 more
TL;DR: A comparative analysis of the transcriptomes of murine wild-type and Retinaldehyde Dehydrogenase 2 null-mutant embryos is performed to provide an overview of the gene expression changes resulting from embryonic RA deficiency, and provide new candidate genes and pathways that may help understanding retinoid-dependent molecular events.
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Molars and incisors: show your microarray IDs
Virginie Laugel-Haushalter,Marie Paschaki,Christelle Thibault-Carpentier,Doulaye Dembélé,Pascal Dollé,Agnès Bloch-Zupan,Agnès Bloch-Zupan +6 more
TL;DR: A comparative transcriptomic analysis of developing murine lower incisors, mandibular molars and maxillary molars at the developmental cap stage allowed us to build several regulatory networks that may distinguish incisor versus molar identity, and may be useful for further investigations of these tooth-specific ontogenetic programs.
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Sox2 acts as a rheostat of epithelial to mesenchymal transition during neural crest development
Nikolaos Mandalos,Muriel Rhinn,Zoraide Granchi,Ioannis Karampelas,Thimios A. Mitsiadis,Aris N. Economides,Pascal Dollé,Eumorphia Remboutsika +7 more
TL;DR: A novel role for Sox2 is suggested as a regulator of the epithelial to mesenchymal transitions (EMT) that are important for the cell flow in the developing head.
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Retinoic Acid-Dependent Signaling Pathways and Lineage Events in the Developing Mouse Spinal Cord
Marie Paschaki,Song Chang Lin,Rebecca Lee Yean Wong,Richard H. Finnell,Pascal Dollé,Karen Niederreither +5 more
TL;DR: It is proposed that RA has separable functions in the developing spinal cord to maintain high levels of FGF and Notch signaling and drive stem cell differentiation, thus restricting both the numbers and the pluripotent character of neural stem cells.
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Expression of T:G mismatch-specific thymidine-DNA glycosylase and DNA methyl transferase genes during development and tumorigenesis.
TL;DR: TDG transcripts were uniformly and ubiquitously expressed from 7.5–13.5 days post-coitum, but were then markedly enriched in specific tissues of the developing fetus, and strongly correlated with those of the methyl transferase (MTase) gene, coding for the enzyme which specifically methylates CpG dinucleotides, and the p53 tumour suppressor gene.