Pasi Kankaanpää

TL;DR: The data show that probiotics can be used as innovative tools to alleviate intestinal inflammation, normalize gut mucosal dysfunction, and down-regulate hypersensitivity reactions and suggest that specific immunomodulatory properties of probiotic bacteria should be characterized when developing clinical applications for extended target populations.

TL;DR: The results indicate that the action of probiotics in the gut may be modulated by dietary PUFA.

TL;DR: This study demonstrates that TAT-SA-PPAA is a potential non-viral vector to be utilized in protein therapeutics to deliver biotinylated molecules both into cytoplasm and nucleus of human cells.

TL;DR: BioImageXD allows simple construction of processing pipelines and should enable biologists to perform challenging analyses of complex processes, and is demonstrated in a study of integrin clustering in response to selected inhibitors.

TL;DR: Alpha 2 beta 1 integrin was found inside caveolae and subsequently internalized into caveosome-like perinuclear structures, and the internalization process, unlike cluster formation or lateral redistribution, was dependent on protein kinase C alpha activity.