P
Patoomratana Tuchinda
Researcher at Mahidol University
Publications - 180
Citations - 3222
Patoomratana Tuchinda is an academic researcher from Mahidol University. The author has contributed to research in topics: Nucleophilic addition & Enantioselective synthesis. The author has an hindex of 28, co-authored 175 publications receiving 2783 citations. Previous affiliations of Patoomratana Tuchinda include University of Illinois at Chicago.
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Journal ArticleDOI
Radical Cyclization/ipso‐1,4‐Aryl Migration Cascade: Asymmetric Synthesis of 3,3‐Difluoro‐2‐propanoylbicyclo[3.3.0]octanes
Watcharaporn Thaharn,Darunee Soorukram,Chutima Kuhakarn,Patoomratana Tuchinda,Vichai Reutrakul,Manat Pohmakotr +5 more
TL;DR: A novel method for the asymmetric synthesis of 3,3-difluoro-2-propanoylbicyclo-[3.3.0]octanes involves an unprecedented intramolecular radical cyclization/ipso-1,4-aryl migration cascade.
Journal ArticleDOI
Anti-HIV-1 protostane triterpenes and digeranylbenzophenone from trunk bark and stems of Garcinia speciosa
Vatcharin Rukachaisirikul,Phanruethai Pailee,Assdhawut Hiranrat,Patoomratana Tuchinda,Chalobon Yoosook,Jittra Kasisit,Walter C. Taylor,Vichai Reutrakul +7 more
TL;DR: This work represents the first report on the anti-HIV-1 activities of the protostane triterpenes and was active in HIV-1 RT assay, but toxic in the syncytium assay.
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Dichapetalin-type triterpenoids and lignans from the aerial parts of Phyllanthus acutissima.
Patoomratana Tuchinda,Jittra Kornsakulkarn,Manat Pohmakotr,Palangpon Kongsaeree,Samran Prabpai,Chalobon Yoosook,Jitra Kasisit,Chanita Napaswad,Samaisukh Sophasan,Vichai Reutrakul +9 more
TL;DR: Chemical investigation of the aerial parts of Phyllanthus acutissima resulted in the isolation of five new dichapetalin-type triterpenoids, acutISSimatriterpenes A-E, and two new lignans, acUTissimalignans A and B, along with two known lignan and three known ellagic acid derivatives.
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Cytotoxic coumarins from Mammea harmandii.
Vichai Reutrakul,Pornsiri Leewanich,Patoomratana Tuchinda,Manat Pohmakotr,Thaworn Jaipetch,Samaisukh Sophasan,Thawatchai Santisuk +6 more
TL;DR: Two new naturally occurring coumarins, isomesuol and mammearin A, together with nine known Mammea coumarin 3-11 were isolated from the EtOAc extract of the leaves and twigs of MammeA harmandii and showed cytotoxicity against a panel of mammalian cancer cell lines.
Journal ArticleDOI
α,α-Difluoro-α-phenylsulfanylmethyl carbanion equivalent: a novel gem-difluoromethylenation of carbonyl compounds
Manat Pohmakotr,Kanhokthron Boonkitpattarakul,Winai Ieawsuwan,Suwatchai Jarussophon,Nongnaphat Duangdee,Patoomratana Tuchinda,Vichai Reutrakul +6 more
TL;DR: In this paper, an α,α-difluoro-α-phenylsulfanyl-α trimethylsilylmethane (PhSCF2SiMe3) has been demonstrated as an α-carbanion equivalent.