P
Patoomratana Tuchinda
Researcher at Mahidol University
Publications - 180
Citations - 3222
Patoomratana Tuchinda is an academic researcher from Mahidol University. The author has contributed to research in topics: Nucleophilic addition & Enantioselective synthesis. The author has an hindex of 28, co-authored 175 publications receiving 2783 citations. Previous affiliations of Patoomratana Tuchinda include University of Illinois at Chicago.
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Journal ArticleDOI
Anti HIV-1 Flavonoid Glycosides from Ochna integerrima
Vichai Reutrakul,Niwat Ningnuek,Manat Pohmakotr,Chalobon Yoosook,Chanita Napaswad,Jitra Kasisit,Thawatchai Santisuk,Patoomratana Tuchinda +7 more
TL;DR: Bioassay-guided fractionation of the anti-HIV-1 active EtOAc extract from leaves and twigs of Ochna integerrima led to the isolation of five new flavonoid glycosides 1 - 5, five known flavonoids 6 - 10, and two known flavonsides 11 and 12, determined based on spectroscopic analyses.
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Non-phenolic linear diarylheptanoids from Curcuma xanthorrhiza: a novel type of topical anti-inflammatory agents: structure - activity relationship
P. Claeson,U. Pongprayoon,T. Sematong,Patoomratana Tuchinda,Vichai Reutrakul,P. Soontornsaratune,Walter C. Taylor +6 more
TL;DR: The non-phenolic linear 1,7-diarylheptanoids are proposed to represent a novel class of topical anti-inflammatory agents based on findings in the murine model of ethyl phenylpropiolate-induced ear edema.
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Cytotoxic and anti-HIV-1 constituents of Gardenia obtusifolia and their modified compounds
Patoomratana Tuchinda,Wilart Pompimon,Vichai Reutrakul,Manat Pohmakotr,Chalobon Yoosook,Natedao Kongyai,Samaisukh Sophasan,Kulawee Sujarit,Suchart E Upathum,Thawatchai Santisuk +9 more
TL;DR: In this article, the structures of five known flavones 5,7,4′-trihydroxy-3,8,3-tri-methoxyflavone (5), 5, 7, 4, 6, 7 and 5, 3,6,7-8-trimethoxyFLavone have been identified from the leaves and twigs of Gardenia obtusifolia.
Journal ArticleDOI
Cytotoxic arylnaphthalide lignan glycosides from the aerial parts of Phyllanthus taxodiifolius.
Patoomratana Tuchinda,Anawat Kumkao,Manat Pohmakotr,Samaisukh Sophasan,Thawatchai Santisuk,Vichai Reutrakul +5 more
TL;DR: Compounds and were inactive in all tested cell lines and exhibited potent cytotoxic activities with GI50 values in the range of 10(-7)-10(-9) M in five cultured mammalian cancer cell lines while the new compound showed moderate activity (GI50 in the order of 10 (-6) M).
Journal ArticleDOI
Anti-HIV-1 constituents from leaves and twigs of Cratoxylum arborescens.
Vichai Reutrakul,Waraporn Chanakul,Manat Pohmakotr,Thaworn Jaipetch,Chalobon Yoosook,Jittra Kasisit,Chanita Napaswat,Thawatchai Santisuk,Samran Prabpai,Palangpon Kongsaeree,Patoomratana Tuchinda +10 more
TL;DR: Two new xanthones, 1,3,8-trihydroxy-2,4-dimethoxyxanthone (1) and 1,7-dihydroxylup-20(29)-en-30-oic acid (2) and twelve known compounds 3 - 14 were isolated from leaves and twigs of Cratoxylum arborescens, showing anti-HIV-1 activities in the syncytium assay.