P
Patoomratana Tuchinda
Researcher at Mahidol University
Publications - 180
Citations - 3222
Patoomratana Tuchinda is an academic researcher from Mahidol University. The author has contributed to research in topics: Nucleophilic addition & Enantioselective synthesis. The author has an hindex of 28, co-authored 175 publications receiving 2783 citations. Previous affiliations of Patoomratana Tuchinda include University of Illinois at Chicago.
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Journal ArticleDOI
Nucleophilic trifluoromethylation of anhydrides employing (trifluoromethyl)trimethylsilane: Synthesis of γ-trifluoromethylated γ-butyrolactones
Chonticha Masusai,Darunee Soorukram,Chutima Kuhakarn,Patoomratana Tuchinda,Vichai Reutrakul,Manat Pohmakotr +5 more
TL;DR: Fluoride-catalyzed nucleophilic trifluoromethylation of acid anhydrides using CF 3 SiMe 3 provided the corresponding γ-hydroxy-γ-trifluorsomethsyl-γ -butyrolactones as mentioned in this paper.
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Neuroprotection of N-benzylcinnamide on scopolamine-induced cholinergic dysfunction in human SH-SY5Y neuroblastoma cells
Nicha Puangmalai,Wipawan Thangnipon,Rungtip Soi-ampornkul,Nirut Suwanna,Patoomratana Tuchinda,Saksit Nobsathian +5 more
TL;DR: The underlying mechanisms of scopolamine-induced Alzheimer's disease-like cellular dysfunctions are revealed, which provide evidence for developing drugs for the treatment of this debilitating disease.
Journal ArticleDOI
Synthesis of gem‐Difluoromethylenated Spiro‐γ‐butyrolactones by Employing PhSCF2Si(CH3)3 as a gem‐Difluoromethylenating Agent
Adisak Chatupheeraphat,Darunee Soorukram,Chutima Kuhakarn,Patoomratana Tuchinda,Vichai Reutrakul,Chaveng Pakawatchai,Saowanit Saithong,Manat Pohmakotr +7 more
TL;DR: In this article, PhSCF2TMS was utilized as a useful gem-difluoromethylene building block for the synthesis of spiro-γ-butyrolactones.
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α,α-Difluoro-α-phenylsulfanyl-α-trimethylsilylmethane as a difluoromethyl building block: A general strategy to α,α-difluoromethyl aryl ketones
Kanhokthron Boonkitpattarakul,Darunee Soorukram,Patoomratana Tuchinda,Vichai Reutrakul,Manat Pohmakotr +4 more
TL;DR: In this paper, the utility of α,α-difluoromethyl aryl ketones was demonstrated using PhSCF 2 SiMe 3 with aromatic aldehydes followed by flash vacuum pyrolytic elimination.
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Asymmetric synthesis of pentenomycin I, epipentenomycin I, and their analogs
TL;DR: The synthetic utility of the intramolecular acylation of α-sulfinyl carbanions as an efficient and general synthetic approach for the preparation of (−)-pentenomycin I (1) and (−)-epipentenomycin I (5) and their enantiomers (ent-1 and ent-5) has been demonstrated as mentioned in this paper.