Patricia D. Finn

TL;DR: To identify targets for leptin’s action, in situ hybridization and computerized imaging was used to map leptin receptor (Ob-R) messenger RNA (mRNA) distribution and Ob-R mRNA was observed in the anterior pituitary and several areas of the brain, including the arcuate and ventromedial nuclei of the hypothalamus.

TL;DR: An androgen receptor (AR) ligand that maintains expected anabolic activities with substantially diminished activity in the prostate and demonstrates the important role of the AR and androgens in mediating a number of beneficial effects in bone, muscle, and sexual function independent from the conversion of androgens into estrogenic ligands.

TL;DR: Observations suggest that leptin may act on serotonergic cells to mediate some of its effects on ingestive behavior, metabolism, and reproduction.

TL;DR: Results are consistent with the hypothesis that the induction of c-fos gene expression in GnRH neurons leads to an increase in galanin gene expression, and that the sustained increase in Galanin mRNA levels in Gn RH neurons reflects either the need to replenish galanIn stores that are depleted at the time of the LH surge or the involvement of galan in with physiological events that occur on the day of estrus.

TL;DR: It is suggested that galanin induces LH release in primates, but galan in may not act directly on hypothalamic GnRH neurons.