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Patricia Parsons-Wingerter
Researcher at Glenn Research Center
Publications - 24
Citations - 620
Patricia Parsons-Wingerter is an academic researcher from Glenn Research Center. The author has contributed to research in topics: Angiogenesis & Blood vessel. The author has an hindex of 10, co-authored 21 publications receiving 497 citations. Previous affiliations of Patricia Parsons-Wingerter include Ames Research Center.
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Journal ArticleDOI
The Cardioprotective Protein Apolipoprotein A1 Promotes Potent Anti-tumorigenic Effects
Maryam Zamanian-Daryoush,Daniel J. Lindner,Thomas C. Tallant,Zeneng Wang,Jennifer A. Buffa,Elizabeth Klipfell,Yvonne Parker,Denise A. Hatala,Patricia Parsons-Wingerter,Pat Rayman,Mohamed Sharif S Yusufishaq,Edward A. Fisher,Jonathan D. Smith,Jim Finke,Joseph A. DiDonato,Stanley A Hazen +15 more
TL;DR: A potent immunomodulatory role for apoA1 in the tumor microenvironment is revealed, altering tumor-associated macrophages from a pro-tumor M2 to an anti-t tumor M1 phenotype, which may hold benefit as a potential cancer therapeutic.
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VESGEN 2D: Automated, User‐Interactive Software for Quantification and Mapping of Angiogenic and Lymphangiogenic Trees and Networks
Mary B. Vickerman,Patricia A. Keith,Terri L. McKay,Dan J. Gedeon,Michiko Watanabe,Monica M. Montano,Ganga Karunamuni,Peter K. Kaiser,Jonathan E. Sears,Quteba Ebrahem,Daniela Ribita,Alan Hylton,Patricia Parsons-Wingerter +12 more
TL;DR: Application of VESGEN 2D to angiogenic and lymphangiogenic tissues that includes the human and murine retina, embryonic coronary vessels, and avian chorioallantoic membrane is reviewed.
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Probiotic Yeast Inhibits VEGFR Signaling and Angiogenesis in Intestinal Inflammation
Xinhua Chen,Guoxun Yang,Joo Hye Song,Huansheng Xu,Dan Li,Jeff Goldsmith,Huiyan Zeng,Patricia Parsons-Wingerter,Hans Christian Reinecker,Ciaran P. Kelly +9 more
TL;DR: Findings indicate that the probiotic yeast S boulardii can modulate angiogenesis to limit intestinal inflammation and promote mucosal tissue repair by regulating VEGFR signaling.
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A VEGF165-induced phenotypic switch from increased vessel density to increased vessel diameter and increased endothelial NOS activity
Patricia Parsons-Wingerter,Unni M. Chandrasekharan,Terri L. McKay,Krishnan Radhakrishnan,Paul E. DiCorleto,Brian Albarran,Andrew G. Farr +6 more
TL;DR: VEGF(165) induced a phenotypic switch from increased vessel density associated with low VEGF concentration, to increased vessel diameter and increased eNOS activity at high V EGF concentration.
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Selective inhibition of angiogenesis in small blood vessels and decrease in vessel diameter throughout the vascular tree by triamcinolone acetonide.
Terri L. McKay,Dan J. Gedeon,Mary B. Vickerman,Alan Hylton,Daniela Ribita,Harry H. Olar,Peter K. Kaiser,Patricia Parsons-Wingerter +7 more
TL;DR: By VESGEN analysis, TA selectively inhibited the angiogenesis of smaller blood vessels, but decreased the vessel diameter of all vessels within the vascular tree.