Michiko Watanabe

TL;DR: Observations suggest that functional loss of Cited2 is responsible for defects in heart and neural tube development, in part because of the modulation of HIF-1 transcriptional activities in the absence of Cite2.

TL;DR: Immunocytochemical evidence is presented which suggests that all classes of macroglia express N-CAM/D2-C AM antigenic determinants on their surfaces and immunochemical analyses which indicate that the molecules expressed by purified astrocytes are closely similar, or identical, to at least some forms of N- cams obtained from whole brain or purified neurones.

TL;DR: This marks the first time that the preseptated embryonic avian heart has been imaged in 4D without the aid of gating and the firsttime it has been viewed in cross section during looping with extremely high temporal resolution, enabling the observation of morphological dynamics of the beating heart during systole.

TL;DR: It is suggested that the craniofacial and cardiac outflow tract defects observed in patients with a distal 22q11.2 micro-deletion are explained by deficiencies in neural crest autonomous ERK2 signaling.

TL;DR: At low radiant exposures, embryonic quail hearts were reliably paced in vivo without detectable damage to the tissue, indicating that OP has great potential as a tool to study embryonic cardiac dynamics and development.