P
Patrick J. Roach
Researcher at Pacific Northwest National Laboratory
Publications - 23
Citations - 3672
Patrick J. Roach is an academic researcher from Pacific Northwest National Laboratory. The author has contributed to research in topics: Desorption electrospray ionization & Mass spectrometry. The author has an hindex of 22, co-authored 23 publications receiving 3267 citations. Previous affiliations of Patrick J. Roach include Pennsylvania State University & Environmental Molecular Sciences Laboratory.
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Journal ArticleDOI
Mass spectral molecular networking of living microbial colonies
Jeramie D. Watrous,Patrick J. Roach,Theodore Alexandrov,Theodore Alexandrov,Brandi S. Heath,Jane Y. Yang,Roland D. Kersten,Menno van der Voort,Kit Pogliano,Harald Gross,Jos M. Raaijmakers,Bradley S. Moore,Julia Laskin,Nuno Bandeira,Pieter C. Dorrestein +14 more
TL;DR: The platform presented here provides a significant advancement in the ability to understand the spatiotemporal dynamics of metabolite production in live microbial colonies and communities.
Journal ArticleDOI
Al Cluster Superatoms as Halogens in Polyhalides and as Alkaline Earths in Iodide Salts
Denis E. Bergeron,Denis E. Bergeron,Patrick J. Roach,Patrick J. Roach,A. W. Castleman,A. W. Castleman,N. O. Jones,N. O. Jones,Shiv N. Khanna,Shiv N. Khanna +9 more
TL;DR: Two classes of gas-phase aluminum-iodine clusters have been identified whose stability and reactivity can be understood in terms of the spherical shell jellium model and the potential synthetic utility of superatom chemistry built upon these motifs is addressed.
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Nanospray desorption electrospray ionization: an ambient method for liquid-extraction surface sampling in mass spectrometry
TL;DR: Nanospray desorption electrospray ionization (nano-DESI) mass spectrometry is presented as an ambient pressure liquid extraction-ionization technique for analysis of organic and biological molecules on substrates and its potential for imaging applications is discussed.
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Tissue Imaging Using Nanospray Desorption Electrospray Ionization Mass Spectrometry
TL;DR: The first proof-of-principle experiments indicate the potential of nano-DESI for ambient imaging with a spatial resolution of better than 12 μm, which will enable new imaging mass spectrometry applications in clinical diagnostics, drug discovery, molecular biology, and biochemistry.
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Complementary active sites cause size-selective reactivity of aluminum cluster anions with water.
TL;DR: The size selectivity of aluminum cluster anion reactions with water, which can be attributed to the dissociative chemisorption of water at specific surface sites, is observed.