P
Patrick K. H. Lee
Researcher at City University of Hong Kong
Publications - 111
Citations - 4645
Patrick K. H. Lee is an academic researcher from City University of Hong Kong. The author has contributed to research in topics: Dehalococcoides & Biology. The author has an hindex of 31, co-authored 93 publications receiving 3469 citations. Previous affiliations of Patrick K. H. Lee include University of California, Berkeley.
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Journal ArticleDOI
Mechanisms of Antibacterial Activity of MgO: Non‐ROS Mediated Toxicity of MgO Nanoparticles Towards Escherichia coli
Yu Hang Leung,Alan Man Ching Ng,Alan Man Ching Ng,Xiaoying Xu,Zhiyong Shen,Lee A. Gethings,Mabel Ting Wong,Charis M.N. Chan,Mu Yao Guo,Mu Yao Guo,Yip Hang Ng,Aleksandra B. Djurišić,Patrick K. H. Lee,Wai Kin Chan,Li Hong Yu,David Lee Phillips,Angel P. Y. Ma,Frederick C. Leung +17 more
TL;DR: In this paper, the toxicity of metal oxide nanomaterials and their antimicrobial activity is attracting increasing attention among these materials, MgO is particularly interesting as a low cost, environmentally-friendly material.
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Toxicity of metal oxide nanoparticles: mechanisms, characterization, and avoiding experimental artefacts.
Aleksandra B. Djurišić,Yu Hang Leung,Alan Man Ching Ng,Alan Man Ching Ng,Xiaoying Xu,Patrick K. H. Lee,Natalie Degger,Rudolf S.S. Wu +7 more
TL;DR: The relationship between the material properties and toxicity appears to be complex and diifficult to understand, which is partly due to incomplete characterization of the nanomaterial, and possibly due to experimental artefacts in the characterization of it and/or its interactions with living organisms.
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Influence of vitamin B12 and cocultures on the growth of Dehalococcoides isolates in defined medium.
TL;DR: It is demonstrated that the growth of D. ethenogenes strain 195 in defined medium can be optimized by providing high concentrations of vitamin B12 and that this strain can be grown to higher densities in cocultures with fermenters that convert lactate to generate the required hydrogen and acetate and that may enhance the availability ofitamin B12.
Journal ArticleDOI
Quantifying genes and transcripts to assess the in situ physiology of "Dehalococcoides" spp. in a trichloroethene-contaminated groundwater site.
Patrick K. H. Lee,Tamzen W. Macbeth,Kent S. Sorenson,Rula A. Deeb,Lisa Alvarez-Cohen,Lisa Alvarez-Cohen +5 more
TL;DR: Results from this study demonstrate that quantification of biomarker dynamics at field sites can provide useful information about the in situ physiology of Dehalococcoides strains and their associated activity.
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An internal reference technique for accurately quantifying specific mRNAs by real-time PCR with application to the tceA reductive dehalogenase gene.
TL;DR: Results show that exposure to TCE or cis-1,2-dichloroethene resulted in 25-fold-higher quantities of tceA mRNA than exposure to vinyl chloride or chlorinated ethene starvation.