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Patrizia Brigidi
Researcher at University of Bologna
Publications - 273
Citations - 21389
Patrizia Brigidi is an academic researcher from University of Bologna. The author has contributed to research in topics: Gut flora & Microbiome. The author has an hindex of 69, co-authored 243 publications receiving 17599 citations. Previous affiliations of Patrizia Brigidi include University of Catania & Leiden University Medical Center.
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Journal ArticleDOI
Intestinal microbiota is a plastic factor responding to environmental changes
TL;DR: A mechanistic comprehension of the dynamics involved in this process is needed to deal more rationally with the role of the human intestinal microbiota in health and disease.
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Gut microbiota changes in the extreme decades of human life: a focus on centenarians.
Aurelia Santoro,Rita Ostan,Marco Candela,Elena Biagi,Patrizia Brigidi,Miriam Capri,Claudio Franceschi +6 more
TL;DR: It is argued that comparison among studies on centenarians—the best model of healthy aging and longevity—recruited from different geographical areas/populations (different genetics and dietary habits) can help to disentangle the contribution of aging and non-aging-related variables to GM remodeling with age.
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Functional intestinal microbiome, new frontiers in prebiotic design.
TL;DR: This review focuses on the revision of the prebiotic concept in the context of the new metagenomic era, and the integration of the functional analyses provided by the massive sequencing of bacterial genomes and metagenomes will allow the rational production of a desired prebiotics molecule with specific functional properties.
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Gut microbiota, metabolome and immune signatures in patients with uncomplicated diverticular disease
Giovanni Barbara,Eleonora Scaioli,Maria Raffaella Barbaro,Elena Biagi,Luca Laghi,Cesare Cremon,Giovanni Marasco,Antonio Colecchia,Gianfranco Picone,Nunzio Salfi,Francesco Capozzi,Patrizia Brigidi,Davide Festi +12 more
TL;DR: Patients with colonic diverticular disease show depletion of microbiota members with anti-inflammatory activity associated with mucosal macrophage infiltration, and metabolome profiles were linked to inflammatory pathways and gut neuromotor dysfunction and showed the ability to discriminate diverticular subgroups and controls.
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Effect of probiotic strains on interleukin 8 production by HT29/19A cells.
Karen M. Lammers,Ulf Helwig,Erwin Swennen,Fernando Rizzello,A. Venturi,Elisabetta Caramelli,Michael A. Kamm,Patrizia Brigidi,Paolo Gionchetti,Massimo Campieri +9 more
TL;DR: The results suggest that probiotic Gram-positive bacteria and E. coli Nissle 1917 may exert their beneficial effects on the host by a different mechanism of action.