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Patrizia Campolongo
Researcher at Sapienza University of Rome
Publications - 117
Citations - 6552
Patrizia Campolongo is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Endocannabinoid system & Cannabinoid receptor. The author has an hindex of 40, co-authored 106 publications receiving 5551 citations. Previous affiliations of Patrizia Campolongo include University of Foggia & Ludwig Maximilian University of Munich.
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Journal ArticleDOI
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis
Gabriella Gobbi,Francis Rodriguez Bambico,Regina A. Mangieri,Marco Bortolato,Patrizia Campolongo,Marcello Solinas,Tommaso Cassano,Maria Grazia Morgese,Guy Debonnel,Andrea Duranti,Andrea Tontini,Giorgio Tarzia,Marco Mor,Viviana Trezza,Steven R. Goldberg,Vincenzo Cuomo,Daniele Piomelli +16 more
TL;DR: It is shown that URB597, a selective inhibitor of the enzyme fatty-acid amide hydrolase, which catalyzes the intracellular hydrolysis of the endocannabinoid anandamide, exerts potent antidepressant-like effects in the mouse tail-suspension test and the rat forced-swim test.
Antidepressant-Like Activity and Modulation of Brain Monoaminergic Transmission by Blockade of Anandamide Hydrolysis
Gabriella Gobbi,Francis Rodriguez Bambico,Regina A. Mangieri,Marco Bortolato,Patrizia Campolongo,Tommaso Cassano,Maria Grazia Morgese,Guy Debonnel,Andrea Duranti,A. Tontini,Giorgio Tarzia,Marco Mor,Viviana Trezza,Steven R. Goldberg,Vincenzo Cuomo,Daniele Piomelli +15 more
TL;DR: Gobi et al. as discussed by the authors showed that URB597, a selective inhibitor of the enzyme fatty acid amide hydrolase, which catalyzes the intracellular hydrolysis of the endocannabinoid anandamide, exerts potent antidepressant-like effects in the mouse tail-suspension test and the rat forced-swim test.
Journal ArticleDOI
The Lipid Messenger OEA Links Dietary Fat Intake to Satiety
Gary J. Schwartz,Jin Fu,Giuseppe Astarita,Xiaosong Li,Silvana Gaetani,Patrizia Campolongo,Vincenzo Cuomo,Daniele Piomelli,Daniele Piomelli +8 more
TL;DR: The results suggest that activation of small-intestinal OEA mobilization, enabled by CD36-mediated uptake of dietary oleic acid, serves as a molecular sensor linking fat ingestion to satiety.
Journal ArticleDOI
Endocannabinoids in the rat basolateral amygdala enhance memory consolidation and enable glucocorticoid modulation of memory.
Patrizia Campolongo,Benno Roozendaal,Viviana Trezza,Daniela Hauer,Gustav Schelling,James L. McGaugh,Vincenzo Cuomo +6 more
TL;DR: It is suggested that endocannabinoids in the BLA enhance memory consolidation and suggest that CB1 activity within this brain region is required for enabling glucocorticoid effects on memory consolidation enhancement.
Journal ArticleDOI
Anxiolytic-Like Properties of the Anandamide Transport Inhibitor AM404
Marco Bortolato,Patrizia Campolongo,Regina A. Mangieri,Maria Luisa Scattoni,Roberto Frau,Viviana Trezza,Giovanna La Rana,Roberto Russo,Antonio Calignano,Gian Luigi Gessa,Vincenzo Cuomo,Daniele Piomelli +11 more
TL;DR: A role of anandamide in the regulation of emotion is supported and the an andamide transport system is pointed to as a potential target for anxiolytic drugs.