Patrizia Murino

TL;DR: The results indicate that rifampicin should not be routinely combined with colistin in clinical practice, and that the increased rate of A. baumannii eradication with combination treatment could still imply a clinical benefit.

TL;DR: Lower levels of IL-6 at baseline as well as lower neutrophil to lymphocyte ratio as compared with patients whose COVID-19 did not improve with treatment were associated with sarilumab-responsive disease, suggesting CRP could be a potential biomarker of response to treatment.

TL;DR: CO VID-19 ARDS is associated with clinically relevant uncoupling of right ventricular function from the pulmonary circulation; bedside echocardiography of TAPSE/PASP adds to the prognostic relevance of PaO 2 /FIO 2 in ARDS on COVID-19.

TL;DR: Colistin resistance as determined by BMD was associated with significantly lower mortality among patients with severe CRAB infections and colistin monotherapy wasassociated with a better outcome compared to colist in-meropenem combination therapy.

TL;DR: In vitro synergism between colistin and meropenem via checkerboard method did not translate into clinical benefit, and synergism was not protective against 14-day clinical failure nor 14- day mortality.