G
Giuseppe Giuffre
Publications - 3
Citations - 111
Giuseppe Giuffre is an academic researcher. The author has contributed to research in topics: Acinetobacter baumannii & Colistin. The author has an hindex of 2, co-authored 3 publications receiving 63 citations.
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Journal ArticleDOI
Treatment Outcomes of Colistin- and Carbapenem-resistant Acinetobacter baumannii Infections: An Exploratory Subgroup Analysis of a Randomized Clinical Trial.
Yaakov Dickstein,Jonathan Lellouche,Ma’ayan Amar,David A. Schwartz,Amir Nutman,Vered Daitch,Dafna Yahav,Dafna Yahav,Leonard Leibovici,Anna Skiada,Anastasia Antoniadou,George L. Daikos,Roberto Andini,Rosa Zampino,Emanuele Durante-Mangoni,Johan W. Mouton,Lena E. Friberg,Yael Dishon Benattar,Yael Dishon Benattar,Roni Bitterman,Ami Neuberger,Yehuda Carmeli,Yehuda Carmeli,Mical Paul,Mical Paul,Hiba Zayyad,Fidi Koppel,Yael Zak-Doron,Sergey Altunin,Nizar Andria,Anat Stern,Neta Petersiel,Marina Raines,Amir Karban,Noa Eliakim-Raz,Oren Zusman,Michal Elbaz,Heyam Atamna,Tanya Babich,Amos Adler,Inbar Levi,Ioannis Pavleas,Antigoni Kotsaki,Domenico Iossa,Mariano Bernardo,Giusi Cavezza,Lorenzo Bertolino,Giuseppe Giuffre,Roberto Giurazza,Susanna Cuccurullo,Maria Galdo,Patrizia Murino,Adriano Cristinziano,Antonio Corcione,Pia Clara Pafundi,Johan Mouton,Anders N. Kristoffersson,Ursula Theuretzbacher +57 more
TL;DR: Colistin resistance as determined by BMD was associated with significantly lower mortality among patients with severe CRAB infections and colistin monotherapy wasassociated with a better outcome compared to colist in-meropenem combination therapy.
Journal ArticleDOI
Colistin plus meropenem for carbapenem-resistant Gram-negative infections: in vitro synergism is not associated with better clinical outcomes
Amir Nutman,Jonathan Lellouche,Elizabeth Temkin,George K. Daikos,Anna Skiada,Emanuele Durante-Mangoni,Yael Dishon-Benattar,Yael Dishon-Benattar,Roni Bitterman,Dafna Yahav,Dafna Yahav,Vered Daitch,Vered Daitch,Mariano Bernardo,Domenico Iossa,Oren Zusman,Lena E. Friberg,Johan W. Mouton,Ursula Theuretzbacher,Leonard Leibovici,Leonard Leibovici,Mical Paul,Mical Paul,Yehuda Carmeli,Yael Dishon Benattar,Yaakov Dickstein,Hiba Zayyad,Fidi Koppel,Yael Zak-Doron,Sergey Altunin,Nizar Andria,Ami Neuberger,Anat Stern,Neta Petersiel,Marina Raines,Amir Karban,Noa Eliakim-Raz,Michal Elbaz,Heyam Atamna,Tanya Babich,Amos Adler,Inbar Levi,George L. Daikos,Ioannis Pavleas,Anastasia Antoniadou,Antigoni Kotsaki,Roberto Andini,Giusi Cavezza,Lorenzo Bertolino,Giuseppe Giuffre,Roberto Giurazza,Susanna Cuccurullo,Maria Galdo,Patrizia Murino,Adriano Cristinziano,Antonio Corcione,Rosa Zampino,Pia Clara Pafundi,Johan Mouton,Lena E. Friberg,Anders N. Kristoffersson +60 more
TL;DR: In vitro synergism between colistin and meropenem via checkerboard method did not translate into clinical benefit, and synergism was not protective against 14-day clinical failure nor 14- day mortality.
Journal ArticleDOI
In vivo fitness of carbapenem-resistant Acinetobacter baumannii strains in murine infection is associated with treatment failure in human infections.
Amir Nutman,Amir Nutman,Amir Nutman,Elizabeth Temkin,Elizabeth Temkin,Elizabeth Temkin,Jonathan Lellouche,Nadya Rakovitsky,Amichay Hameir,George L. Daikos,Emanuele Durante-Mangoni,Ioannis Pavleas,Yael Dishon,Yael Dishon,Neta Petersiel,Dafna Yahav,Dafna Yahav,Noa Eliakim,Noa Eliakim,Mariano Bernardo,Domenico Iossa,Lena E. Friberg,Ursula Theuretzbacher,Leonard Leibovici,Leonard Leibovici,Mical Paul,Mical Paul,Yehuda Carmeli,Yehuda Carmeli,Yehuda Carmeli,Yael Dishon Benattar,Yaakov Dickstein,Roni Bitterman,Hiba Zayyad,Fidi Koppel,Yael Zak-Doron,Sergey Altunin,Nizar Andria,Ami Neuberger,Anat Stern,Marina Raines,Amir Karban,Noa Eliakim-Raz,Oren Zusman,Michal Elbaz,Heyam Atamna,Vered Daitch,Tanya Babich,Amos Adler,Inbar Levi,George L. Daikos,Anna Skiada,Anastasia Antoniadou,Antigoni Kotsaki,Roberto Andini,Giusi Cavezza,Lorenzo Bertolino,Giuseppe Giuffre,Roberto Giurazza,Giuseppe Ruocco,Maria Galdo,Patrizia Murino,Adriano Cristinziano,Antonio Corcione,Rosa Zampino,Johan W. Mouton,Lena E. Friberg +66 more
TL;DR: In this article, the authors examined whether in-vivo fitness of CRAB strains is associated with clinical outcomes in patients with CRAB infections, and they used mixed-effects logistic regression to test the association between fitness and the two outcomes.