P
Paul D. Blumenthal
Researcher at Stanford University
Publications - 202
Citations - 9295
Paul D. Blumenthal is an academic researcher from Stanford University. The author has contributed to research in topics: Abortion & Population. The author has an hindex of 39, co-authored 191 publications receiving 8240 citations. Previous affiliations of Paul D. Blumenthal include University of Pittsburgh & University of Baltimore.
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Journal ArticleDOI
Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse.
Ye Zhang,Steven A. Sloan,Laura E. Clarke,Christine Caneda,Colton A. Plaza,Paul D. Blumenthal,Hannes Vogel,Gary K. Steinberg,Michael S. B. Edwards,Gordon Li,John A. Duncan,Samuel H. Cheshier,Lawrence M. Shuer,Edward F. Chang,Gerald A. Grant,Melanie Hayden Gephart,Ben A. Barres +16 more
TL;DR: The development of an immunopanning method to acutely purify astrocytes from fetal, juvenile, and adult human brains and to maintain these cells in serum-free cultures is reported, finding that human astroCytes have abilities similar to those of murine astroicytes in promoting neuronal survival, inducing functional synapse formation, and engulfing synaptosomes.
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Derivation of pluripotent stem cells from cultured human primordial germ cells
Michael J. Shamblott,Joyce Axelman,Shunping Wang,Elizabeth M. Bugg,John W. Littlefield,Peter J. Donovan,Paul D. Blumenthal,George R. Huggins,John D. Gearhart +8 more
TL;DR: In this article, a set of primordial germ cells (PGCs, 5-9 weeks postfertilization) were cultured on mouse STO fibroblast feeder layers in the presence of human recombinant leukemia inhibitory factor (HILI) and forskolin.
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Human embryonic germ cell derivatives express a broad range of developmentally distinct markers and proliferate extensively in vitro
Michael J. Shamblott,Joyce Axelman,John W. Littlefield,Paul D. Blumenthal,George R. Huggins,Yan Cui,Linzhao Cheng,John D. Gearhart +7 more
TL;DR: The growth and expression characteristics of EB-derived cells suggest that they are relatively uncommitted precursor or progenitor cells, suited to studies of human cell differentiation and may play a role in future transplantation therapies.
Journal ArticleDOI
Derivation of pluripotent stem cells from cultured human primordial germ cells
Michael J. Shamblott,Joyce Axelman,Shunping Wang,Elizabeth M. Bugg,John W. Littlefield,Peter J. Donovan,Paul D. Blumenthal,George R. Huggins,John D. Gearhart +8 more
TL;DR: Based on their origin and demonstrated properties, these human PGC-derived cultures meet the criteria for pluripotent stem cells and most closely resemble EG cells.
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A Systematic Review Evaluating Health-Related Quality of Life, Work Impairment, and Health-Care Costs and Utilization in Abnormal Uterine Bleeding
TL;DR: A systematic review of the medical literature found that women with AUB have HRQoL below the 25th percentile of that for the general female population within a similar age range and the conservatively estimated annual direct and indirect economic costs of AUB were approximately $1 billion and $12 billion, respectively.