Hannes Vogel

TL;DR: P63 is essential for several aspects of ectodermal differentiation during embryogenesis, including hair follicles, teeth and mammary glands, which are absent in p63-deficient mice.

TL;DR: The development of an immunopanning method to acutely purify astrocytes from fetal, juvenile, and adult human brains and to maintain these cells in serum-free cultures is reported, finding that human astroCytes have abilities similar to those of murine astroicytes in promoting neuronal survival, inducing functional synapse formation, and engulfing synaptosomes.

TL;DR: In vivo optogenetic techniques in awake, behaving mice are used to provide direct evidence that neuronal activity regulates changes in myelin-forming cells within an active circuit, suggesting that adaptive changes inMyelin-form cells represent a type of behaviorally relevant neural plasticity.

TL;DR: Observations indicate that SOD2 deficiency causes increased susceptibility to oxidative mitochondrial injury in central nervous system neurons, cardiac myocytes, and other metabolically active tissues after postnatal exposure to ambient oxygen concentrations.

TL;DR: It is shown that inhibition of Drosophila Pink1 function results in energy depletion, shortened lifespan, and degeneration of select indirect flight muscles and dopaminergic neurons, and the level of Parkin protein is significantly reduced in dPink1 RNA interference animals.