Paul Milligan

TL;DR: This work has studied spatial distribution of herds of cattle in relation to tsetse in The Gambia and calculated an index of challenge based on the ratio of vectors to hosts over the livestock ranging area that is strongly correlated with estimates of the force of infection calculated from the incidence of infection in susceptible zebu.

TL;DR: The sensitivity of P. falciparum to SMC drugs should be regularly monitored in areas deploying this intervention, as the prevalence of genotypes associated with resistance to either SP or AQ was lower in SMC areas due to the reduced number of parasitaemia individuals.

TL;DR: Simple amendments to current AQ dosing schedules based on the child's age could substantially increase dosing accuracy and thus improve the tolerability of IPTc using SP-amodiaquine in situations where weighing the child is impractical.

TL;DR: This analysis supports the WHO recommendation for coadministration of IPTi with sulfadoxine-pyrimethamine to infants at the time of the second and third doses of DTP and measles vaccination, in areas of sub-Saharan Africa with moderate to high malaria transmission and where malaria parasites are sensitive to these drugs.

TL;DR: In this article, a cost-effectiveness and cost-savings analysis of a large-scale, multi-country seasonal malaria chemoprevention (SMC) campaign with sulfadoxine-pyrimethamine plus amodiaquine for children younger than 5 years in seven countries in the Sahel subregion (Burkina Faso, Chad, Guinea, Mali, Niger, Nigeria, and The Gambia) in 2016 is presented.