Jean-François Trape

TL;DR: It is shown that since the late 1980s convincing evidence of a major public health impact of the spread of chloroquine resistance has been available and there is an urgent need to change treatment policies in Africa.

TL;DR: Findings suggest that the spread of chloroquine resistance has had a dramatic impact on the level of malaria mortality in most epidemiological contexts in tropical Africa.

TL;DR: The findings suggest that sterile immunity and clinical protection are never fully achieved in humans continuously exposed since birth to intense transmission.

TL;DR: It is shown that additional conservation actions are needed to effectively protect reptiles, particularly lizards and turtles, and that adding reptile knowledge to a global complementarity conservation priority scheme identifies many locations that consequently become important.

TL;DR: Increasing pyrethroid resistance of A gambiae and increasing susceptibility of older children and adults, probably due to decreasing immunity, caused the rebound and age shift of malaria morbidity.