P
Pauline D. Scanlan
Researcher at University College Cork
Publications - 39
Citations - 3536
Pauline D. Scanlan is an academic researcher from University College Cork. The author has contributed to research in topics: Population & Blastocystis. The author has an hindex of 23, co-authored 38 publications receiving 3030 citations. Previous affiliations of Pauline D. Scanlan include National University of Ireland & University of Oxford.
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Journal ArticleDOI
Rapid and Noninvasive Metabonomic Characterization of Inflammatory Bowel Disease
Julian R. Marchesi,Elaine Holmes,Fatima Khan,Sunil Kochhar,Pauline D. Scanlan,Fergus Shanahan,Ian D. Wilson,Yulan Wang +7 more
TL;DR: The first characterization of fecal extracts obtained from patients with CD and UC is presented by employing a noninvasive metabonomics approach, which combines high resolution 1H NMR spectroscopy and multivariate pattern recognition techniques, suggesting changes in the gut microbial community.
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Culture-Independent Analyses of Temporal Variation of the Dominant Fecal Microbiota and Targeted Bacterial Subgroups in Crohn's Disease
TL;DR: Significant changes are observed in two functionally important mutualistic groups of bacteria, viz., Clostridium and Bacteroides spp.
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Micro-eukaryotic diversity of the human distal gut microbiota: qualitative assessment using culture-dependent and -independent analysis of faeces.
TL;DR: Eukaryotic diversity of the human gut is low, largely temporally stable and predominated by different subtypes of Blastocystis, and specific analyses of the fungal populations indicate that a disparity exists between the cultivable fraction, which is dominated by Candida sp, and culture-independent analysis.
Journal ArticleDOI
Host–parasite coevolutionary arms races give way to fluctuating selection
Alex R. Hall,Pauline D. Scanlan,Andrew D. Morgan,Andrew D. Morgan,Angus Buckling,Angus Buckling +5 more
TL;DR: Phenotypic data from coevolving populations of the bacterium Pseudomonas fluorescens SBW25 and parasitic phageSBW25Φ2 and genetic data from the phage tail fibre gene are used to show that arms race dynamics, typical of short-term studies, decelerate over time.
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Culture-independent analysis of the gut microbiota in colorectal cancer and polyposis.
Pauline D. Scanlan,Fergus Shanahan,Yvonne Clune,John Kevin Collins,Gerald C. O'Sullivan,Micheal O'Riordan,Elaine Holmes,Yulan Wang,Julian R. Marchesi +8 more
TL;DR: The intestinal microbiota and their metabolites are significantly altered in both colorectal cancer and polypectomized subjects compared with controls, and a clear division in the metabonome was observed.