Pei-Pei Xie

TL;DR: The highly atroposelective synthesis via a C−H functionalization strategy of axially chiral styrenes with an open-chained alkene with potent application of the styrene atropisomers is reported.

TL;DR: Experimental and computational studies on the reaction mechanism suggest a novel concerted proton and two-electron transfer process for the allylic C-H cleavage and reveal that the Z/ E- and regioselectivities are governed by the geometry and coordination pattern of nucleophiles.

TL;DR: This paper describes the first rhodium(III)-catalyzed asymmetric borylative cyclization of cyclohexadienone-tethered mono-, 1,1-di- and (E)-1,2- di-substituted alkenes (1,6-dienes), affording optically pure cis-bicyclic skeletons bearing three or four contiguous stereocenters with high yields and excellent diastereoselectivities.

TL;DR: In this paper, a Cp*Co(III)-catalyzed asymmetric hydroarylation of unactivated aliphatic terminal alkenes assisted by a new type of tailor-made amino acid ligands was reported.

TL;DR: This paper reports a general and efficient method for accessing C–N atropisomers through an axial-to-axial chirality transfer strategy based on palladium/chiral norbornene cooperative catalysis and elucidated by density functional theory calculations.