Pengcheng Ma

TL;DR: Lithium hexamethyldisilazide is used to initiate α-amino acid N-carboxyanhydride polymerizations that is very fast and can be conducted in an open vessel, and rapid synthesis of polypeptide libraries for high-throughput functional screening.

TL;DR: It is demonstrated that random copolymers of heterochiral poly-β-peptides, without the need for defined secondary structures, can mimic the antimicrobial HDP, implying the potential application of these poly- β-peptic as new antimicrobial agents to tackle drug resistant antimicrobial infections.

TL;DR: A controllable and water insensitive ring opening polymerization of β-amino acid N-thiocarboxyanhydrides (β-NTAs) that can be operated in open vessels to prepare poly-β-peptides in high yields, with diverse functional groups, variable chain length, narrow dispersity and defined architecture is developed.

TL;DR: It is revealed that β/β杂化多肽聚合物分子刷对多种MRSA’s target audience is under-18s, mainly teenagers.

TL;DR: It is demonstrated that α/β chimeric polypeptide molecular brush (α/β CPMB) exerts potent activities against antibiotic-resistant gram-negative bacteria, implying its potential topical applications in treating biofilms.