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Runhui Liu
Researcher at East China University of Science and Technology
Publications - 67
Citations - 2940
Runhui Liu is an academic researcher from East China University of Science and Technology. The author has contributed to research in topics: Antimicrobial & Polymerization. The author has an hindex of 22, co-authored 66 publications receiving 1681 citations. Previous affiliations of Runhui Liu include Purdue University & University of Wisconsin-Madison.
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Journal ArticleDOI
Versatile Antibacterial Materials: An Emerging Arsenal for Combatting Bacterial Pathogens
TL;DR: The recent advances in developing multifunctional materials for their antibacterial activities together with other functions including “kill‐and‐release” capability, hemocompatibility, cell proliferation promoting properties, and coagulation promoting ability for wound dressing are highlighted.
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Tuning the biological activity profile of antibacterial polymers via subunit substitution pattern.
Runhui Liu,Xinyu Chen,Chakraborty Saswata,Justin J. Lemke,Zvi Hayouka,Clara Chow,Rodney A. Welch,Bernard Weisblum,Kristyn S. Masters,Samuel H. Gellman +9 more
TL;DR: Variation in subunit conformational properties could be generally valuable in the development of synthetic polymers for biological applications, and the α,α,β, β,β-tetramethyl unit is optimal among the subunits the authors have examined.
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Poly(2-Oxazoline)-Based Functional Peptide Mimics: Eradicating MRSA Infections and Persisters while Alleviating Antimicrobial Resistance.
Min Zhou,Yuxin Qian,Jiayang Xie,Wenjing Zhang,Weinan Jiang,Ximian Xiao,Sheng Chen,Chengzhi Dai,Zihao Cong,Zhemin Ji,Ning Shao,Longqiang Liu,Yuequn Wu,Runhui Liu +13 more
TL;DR: This study demonstrated that poly(2-oxazoline) based glycine pseudopeptides can mimic host defense peptide and have potent in vitro and in vivo activities against methicillin-resistant Staphylococcus aureus that cause formidable infections.
Journal ArticleDOI
Nylon-3 Polymers with Selective Antifungal Activity
Runhui Liu,Xinyu Chen,Zvika Hayouka,Chakraborty Saswata,Shaun P. Falk,Bernard Weisblum,Kristyn S. Masters,Samuel H. Gellman +7 more
TL;DR: Nylon-3 polymers based on a novel subunit that display potent antifungal activity and favorable selectivity for fungi are reported.
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Nylon-3 polymers active against drug-resistant Candida albicans biofilms.
TL;DR: The best nylon-3 polymer (poly-βNM) is superior to the antifungal drug fluconazole for all three strains examined and is slightly less effective than amphotericin B (AmpB) for two strains, but the polymer is superior against an AmpB-resistant strain.