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Perttu Permi
Researcher at University of Jyväskylä
Publications - 156
Citations - 4101
Perttu Permi is an academic researcher from University of Jyväskylä. The author has contributed to research in topics: Residual dipolar coupling & Filamin. The author has an hindex of 34, co-authored 149 publications receiving 3600 citations. Previous affiliations of Perttu Permi include University of Helsinki & Harvard University.
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Journal ArticleDOI
SH3 domain ligand binding: What's the consensus and where's the specificity?
Kalle Saksela,Perttu Permi +1 more
TL;DR: The structural basis of non‐consensus SH3 ligand binding and the dominant role of the SH3 domain specificity zone in selective target recognition are discussed, and some of the best‐characterized examples of such interactions are reviewed.
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The structure of the GPIb-filamin A complex.
Fumihiko Nakamura,Regina Pudas,Outi Heikkinen,Perttu Permi,Ilkka Kilpeläinen,Adam D. Munday,John H. Hartwig,Thomas P. Stossel,Jari Ylänne +8 more
TL;DR: The GPIbalpha binding site is mapped to a single domain of FLNa and the structure of this domain and its interaction complex with the corresponding G PIbalpha cytoplasmic domain is resolved, revealing the first atomic structure ofThis class of membrane glycoprotein-cytoskeleton connection.
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Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Has a Unique Mechanism to Rescue Apoptotic Neurons
Maarit Hellman,Urmas Arumäe,Li-Ying Yu,Päivi Lindholm,Johan Peränen,Mart Saarma,Perttu Permi +6 more
TL;DR: A three-dimensional solution structure of human MANF is shown that differs drastically from other neurotrophic factors and confirms that MANF and C-MANF protect neurons intracellularly as efficiently as Ku70.
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Hyperdimensional NMR Spectroscopy with Nonlinear Sampling
TL;DR: The approach reduces data collection time on average by 2 orders of magnitude and builds a model of hyperdimensional (HD) spectrum, which can significantly increase the value of NMR spectroscopy in structural biology, for example, in high-throughput structural genomics applications.
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Arabidopsis RCD1 coordinates chloroplast and mitochondrial functions through interaction with ANAC transcription factors
Alexey Shapiguzov,Alexey Shapiguzov,Julia P. Vainonen,Kerri Hunter,Helena Tossavainen,Helena Tossavainen,Arjun Tiwari,Sari Järvi,Maarit Hellman,Fayezeh Aarabi,Saleh Alseekh,Brecht Wybouw,Katrien Van Der Kelen,Lauri Nikkanen,Julia Krasensky-Wrzaczek,Nina Sipari,Markku Keinänen,Esa Tyystjärvi,Eevi Rintamäki,Bert De Rybel,Jarkko Salojärvi,Frank Van Breusegem,Alisdair R. Fernie,Mikael Brosché,Mikael Brosché,Perttu Permi,Perttu Permi,Eva-Mari Aro,Michael Wrzaczek,Jaakko Kangasjärvi +29 more
TL;DR: RCD1 integrates organellar signaling from chloroplasts and mitochondria to establish transcriptional control over the metabolic processes in both organelles, and is linked to chloroplast signaling by 3-phosphoadenosine 5'-phosphate (PAP).