P
Peter Dieterich
Researcher at Dresden University of Technology
Publications - 38
Citations - 1535
Peter Dieterich is an academic researcher from Dresden University of Technology. The author has contributed to research in topics: Cell migration & Shear stress. The author has an hindex of 16, co-authored 36 publications receiving 1376 citations. Previous affiliations of Peter Dieterich include Queen Mary University of London & University of Würzburg.
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Journal ArticleDOI
Anomalous dynamics of cell migration
TL;DR: By analyzing the trajectories of wild-type and mutated epithelial (transformed Madin–Darby canine kidney) cells, it is shown experimentally that anomalous dynamics characterizes cell migration.
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Migration of human melanoma cells depends on extracellular pH and Na+/H+ exchange.
Christian Stock,Birgit Gassner,Christof R. Hauck,Hannelore Arnold,Sabine Mally,Johannes A. Eble,Peter Dieterich,Albrecht Schwab +7 more
TL;DR: It is proposed that pHe and NHE activity affect migration of human melanoma cells by modulating cell–matrix interactions and is hindered when the interaction is too strong (acidic pHe) or too weak (alkaline pHe or NHE inhibition).
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Endothelial barrier function under laminar fluid shear stress.
Jochen Seebach,Peter Dieterich,Fei Luo,Hermann Schillers,Dietmar Vestweber,Hans Oberleithner,Hans-Joachim Galla,Hans-Joachim Schnittler +7 more
TL;DR: Data show that endothelial monolayers exposed to increased levels of laminar shear stress respond with a shear Stress–dependent regulation of permeability and a reorganization of junction-associated proteins, whereas monolayer integrity remains unaffected.
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Role of actin filaments in endothelial cell-cell adhesion and membrane stability under fluid shear stress
Hans-Joachim Schnittler,Stefan W. Schneider,Hartmann Raifer,Fei Luo,Peter Dieterich,Ingo Just,Klaus Aktories +6 more
TL;DR: It is shown that small disturbances in actin dynamics inhibit shear stress-dependent cell alignment; that depolymerisation of actin filaments increases the solubility of α-catenin, thus resulting in cell dissociation and that actin Filaments of the membrane cytoskeleton are required to protect the cells from haemodynamic injury such as shear Stress.
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The Na +/H + exchanger NHE1 is required for directional migration stimulated via PDGFR-α in the primary cilium
Linda Schneider,Christian Stock,Peter Dieterich,Bo Hammer Jensen,Lotte B. Pedersen,Peter Satir,Albrecht Schwab,Soøren Tvorup Christensen,Stine F. Pedersen +8 more
TL;DR: In this paper, the authors investigated the functional relationship between ciliary PDGFR-α and the Na+/H+ exchanger NHE1 in directional cell migration and found that the primary cilium coordinates platelet-derived growth factor (PDGF) receptor (PDGFR) α-mediated migration in growth-arrested fibroblasts.