P
Peter Koulen
Researcher at Max Planck Society
Publications - 42
Citations - 3581
Peter Koulen is an academic researcher from Max Planck Society. The author has contributed to research in topics: Retina & Inner plexiform layer. The author has an hindex of 26, co-authored 31 publications receiving 3445 citations. Previous affiliations of Peter Koulen include Yale University.
Papers
More filters
Journal ArticleDOI
Polycystin-2 is an intracellular calcium release channel
Peter Koulen,Yiqiang Cai,Lin Geng,Yoshiko Maeda,Sayoko Nishimura,Ralph Witzgall,Barbara E. Ehrlich,Stefan Somlo +7 more
TL;DR: It is shown by single channel studies that polycystin-2 behaves as a calcium-activated, high conductance ER channel that is permeable to divalent cations and thatpolycystic kidney disease results from the loss of a regulated intracellular calcium release signalling mechanism.
Journal ArticleDOI
Glycine and GABA receptors in the mammalian retina.
TL;DR: A great diversity of glycine and GABA receptors in the mammalian retina is found, which might match the plethora of morphological types of amacrine cells and point to subtle differences in synaptic function still to be elucidated.
Journal ArticleDOI
Diversity of glutamate receptors in the mammalian retina
TL;DR: This article will concentrate on glutamate receptors with the intention of reviewing some of the recent data on glutamate receptor expression in the mammalian retina and their possible involvement in retinal function.
Journal ArticleDOI
Immunocytochemical Localization of the Postsynaptic Density Protein PSD-95 in the Mammalian Retina
TL;DR: Electron microscopy showed that PSD-95 was concentrated in processes that were postsynaptic at bipolar cell ribbon synapses (dyads), and double-labeling experiments were performed for PSd-95 and for the NR1 subunit of the NMDA receptor, which were found to be colocalized in synaptic hot spots in the IPL.
Journal ArticleDOI
Nuclear and cytosolic calcium are regulated independently
Maria de Fátima Leite,Edwin C. Thrower,Wihelma Echevarria,Peter Koulen,Keiji Hirata,Anton M. Bennett,Barbara E. Ehrlich,Michael H. Nathanson +7 more
TL;DR: Examining subcellular mechanisms of Ca2+ release in the HepG2 liver cell line found enriched expression of type II InsP3R in the nucleus results in greater sensitivity of the nucleus toInsP3, thus providing a mechanism for independent regulation of Ca1+-dependent processes in this cellular compartment.